4WK9

Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (0.3mM) at 1.10 A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Chitotriosidase-1	polymer	377	42224.3	1	UniProt (Q13231) Pfam (PF00704)	Homo sapiens (Human)	Chitinase-1
2	B (B)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
3	C (A)	water	water		18.0	530	Chemie (HOH)

Sequence modifications

A: 22 - 394 (UniProt: Q13231)

PDB	External Database	Details
Val 388	Pro 388	expression tag
Pro 389	Tyr 389	expression tag
Arg 390	Leu 390	expression tag
Gly 391	Pro 391	expression tag
His 393	Gly 393	expression tag
His 394	Thr 394	expression tag
His 395	-	expression tag
His 396	-	expression tag
His 397	-	expression tag
His 398	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42224.3
Branched	Number of molecules	1
	Total formula weight	424.4
All*	Total formula weight	42648.7

*Water molecules are not included.