4WJL
Structure of human dipeptidyl peptidase 10 (DPPY): a modulator of neuronal Kv4 channels
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Inactive dipeptidyl peptidase 10 | polymer | 719 | 82616.3 | 2 | UniProt (Q8N608) Pfam (PF00930) Pfam (PF00326) | Homo sapiens (Human) | Dipeptidyl peptidase IV-related protein 3,DPRP-3,Dipeptidyl peptidase X,DPP X,Dipeptidyl peptidase-like protein 2,DPL2 |
| 2 | C (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 3 | D, E, G (D, E, G) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 3 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 5 | H, I, J, K (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
A, B: 65 - 783 (UniProt: Q8N608)
| PDB | External Database | Details |
|---|---|---|
| Met 288 | Val 238 | variant |
| Ile 401 | Val 351 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 165232.6 | |
| Branched | Number of molecules | 5 |
| Total formula weight | 2608.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 168725.8 |
