4WJ5
Structure of HLA-A2 in complex with an altered peptide ligands based on Mart-1 variant epitope
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | HLA class I histocompatibility antigen, A-2 alpha chain | polymer | 275 | 31854.2 | 2 | UniProt (P01892) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P04439) In PDB | Homo sapiens (Human) | MHC class I antigen A*2 |
| 2 | B, E | Beta-2-microglobulin | polymer | 100 | 11879.4 | 2 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 3 | C, F | Melanoma antigen recognized by T-cells 1 | polymer | 10 | 985.2 | 2 | UniProt (Q16655) In PDB | Homo sapiens | MART-1,Antigen LB39-AA,Antigen SK29-AA,Protein Melan-A |
| 4 | A, B, D, E | GLYCEROL | non-polymer | 92.1 | 13 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 536 | Chemie (HOH) |
Sequence modifications
B, E: 1 - 99 (UniProt: P61769)
C, F: 0 - 9 (UniProt: Q16655)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Grn 0 | Glu 26 | conflict |
| Nva 1 | Ala 27 | conflict |
| Lph 9 | Val 35 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 89437.5 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1197.2 | |
| All* | Total formula weight | 90634.7 |
