4WI2

Structural mapping of the human IgG1 binding site for FcRn: hu3S193 Fc (wild-type)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Ig gamma-1 chain C region	polymer	208	23634.7	2	UniProt (P01857) Pfam (PF07654)	Homo sapiens (Human)
2	C, D (C, D)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1463.3	2	In PDB GlyTouCan (G80858MF)
3	E, F, G (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
4	H, I (A, B)	water	water		18.0	154	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	47269.4
Branched	Number of molecules	2
	Total formula weight	2926.7
Non-Polymers*	Number of molecules	3
	Total formula weight	186.2
All*	Total formula weight	50382.3

*Water molecules are not included.