4WEU

Co-complex structure of the F4 fimbrial adhesin FaeG variant ad with llama single domain antibody V3

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (D, E)	Anti-F4+ETEC bacteria VHH variable region	polymer	127	14042.6	2	UniProt (R9W3F6) Pfam (PF07686)	Lama glama (Llama)
2	B, C (A, B)	K88 fimbrial protein AD	polymer	277	29217.4	2	UniProt (P14191)	Escherichia coli	K88 antigen,K88 pilin
3	E, F, G, H (D, A, B, E)	water	water		18.0	29	Chemie (HOH)

Sequence modifications

D, E: 801 - 921 (UniProt: R9W3F6)

PDB	External Database	Details
His 922	-	expression tag
His 923	-	expression tag
His 924	-	expression tag
His 925	-	expression tag
His 926	-	expression tag
His 927	-	expression tag

A, B: 19 - 264 (UniProt: P14191)

PDB	External Database	Details
Trp 9	-	expression tag
Met 10	-	expression tag
Thr 11	-	expression tag
Gly 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
Asp 265	-	expression tag
Asn 266	-	expression tag
Lys 267	-	expression tag
Gln 268	-	expression tag
Met 269	-	expression tag
Thr 270	-	expression tag
Gly 271	-	expression tag
Asp 272	-	expression tag
Phe 273	-	expression tag
Asn 274	-	expression tag
Gly 275	-	expression tag
Ser 276	-	expression tag
Val 277	-	expression tag
Asp 278	-	expression tag
Ile 279	-	expression tag
Gly 280	-	expression tag
Gly 281	-	expression tag
Ser 282	-	expression tag
Ile 283	-	expression tag
Thr 284	-	expression tag
Ala 285	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	86520.0
All*	Total formula weight	86520.0

*Water molecules are not included.