4WEM

Co-complex structure of the F4 fimbrial adhesin FaeG variant ac with llama single domain antibody V1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	K88 fimbrial protein AC	polymer	272	28703.9	1	UniProt (L7XD53) UniProt (by SIFTS) (P14190)	Escherichia coli
2	B (B)	Anti-F4+ETEC bacteria VHH variable region	polymer	127	13978.6	1	UniProt (R9W2R6) Pfam (PF07686)	Lama glama (Llama)
3	C, D, E, F (A, B)	PHOSPHATE ION	non-polymer		95.0	4	Chemie (PO4)
4	G, H (A, B)	water	water		18.0	304	Chemie (HOH)

Sequence modifications

A: 19 - 262 (UniProt: L7XD53)

PDB	External Database	Details
Trp 9	-	expression tag
Met 10	-	expression tag
Thr 11	-	expression tag
Gly 12	-	expression tag
His 13	-	expression tag
His 14	-	expression tag
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
Asp 263	-	expression tag
Asn 264	-	expression tag
Lys 275	-	expression tag
Gln 276	-	expression tag
Asp 277	-	expression tag
Phe 278	-	expression tag
Asn 279	-	expression tag
Gly 280	-	expression tag
Ser 281	-	expression tag
Val 282	-	expression tag
Asp 283	-	expression tag
Ile 284	-	expression tag
Gly 285	-	expression tag
Gly 286	-	expression tag
Ser 287	-	expression tag
Ile 288	-	expression tag
Thr 289	-	expression tag
Ala 290	-	expression tag

B: 801 - 921 (UniProt: R9W2R6)

PDB	External Database	Details
His 922	-	expression tag
His 923	-	expression tag
His 924	-	expression tag
His 925	-	expression tag
His 926	-	expression tag
His 927	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42682.5
Non-Polymers*	Number of molecules	4
	Total formula weight	379.9
All*	Total formula weight	43062.3

*Water molecules are not included.