4WA4
The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with oseltamivir carboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Neuraminidase | polymer | 388 | 42936.3 | 1 | UniProt (I6NW33) Pfam (PF00064) In PDB | Influenza A virus (A/harbor seal/Massachusetts/1/2011(H3N8)) | |
| 2 | B | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 3 | A | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 1 | Chemie (G39) | |||
| 4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A: 81 - 468 (UniProt: I6NW33)
| PDB | External Database | Details |
|---|---|---|
| Gln 84 | Asn 84 | conflict |
| Gly 313 | Arg 313 | conflict |
| Asn 396 | Asp 396 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42936.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 324.4 | |
| All* | Total formula weight | 43628.1 |
