4WA4
The crystal structure of neuraminidase from a H3N8 influenza virus isolated from New England harbor seals in complex with oseltamivir carboxylate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuraminidase | polymer | 388 | 42936.3 | 1 | UniProt (I6NW33) | Influenza A virus (A/harbor seal/Massachusetts/1/2011(H3N8)) | |
| 2 | B (B) | alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 367.3 | 1 | In PDB GlyTouCan (G86851RC) | |||
| 3 | C (A) | (3R,4R,5S)-4-(acetylamino)-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylic acid | non-polymer | 284.4 | 1 | Chemie (G39) PubChem (40640967) PubChem (40640969) PubChem (40640971) PubChem (44345914) PubChem (40640973) PubChem (58753598) PubChem (71038155) PubChem (71065667) PubChem (449381) PubChem (4631786) PubChem (95162772) PubChem (121452907) PubChem (124637832) PubChem (129886749) PubChem (134694948) PubChem (137378365) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) PubChem (271) | |||
| 5 | E (A) | water | water | 18.0 | 326 | Chemie (HOH) |
Sequence modifications
A: 81 - 468 (UniProt: I6NW33)
| PDB | External Database | Details |
|---|---|---|
| Gln 84 | Asn 84 | conflict |
| Gly 313 | Arg 313 | conflict |
| Asn 396 | Asp 396 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42936.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 367.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 324.4 | |
| All* | Total formula weight | 43628.1 |
