4W8E
Structure of MST3 with a pyrrolopyrimidine inhibitor (PF-06645342)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase 24 36 kDa subunit | polymer | 291 | 33041.9 | 1 | UniProt (Q9Y6E0) Pfam (PF00069) | Homo sapiens (Human) | Mammalian STE20-like protein kinase 3 N-terminal, MST-3/N |
| 2 | B (A) | 3-{4-[(2R)-2-(5-methyl-1,2,4-oxadiazol-3-yl)morpholin-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}benzonitrile | non-polymer | 387.4 | 1 | Chemie (3JB) | |||
| 3 | C (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 33041.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 387.4 | |
| All* | Total formula weight | 33429.2 |
