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4W7T

Crystal Structure of Hsp90-alpha N-domain Bound to the Inhibitor NVP-HSP990

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Heat shock protein HSP 90-alphapolymer23626601.81UniProt (P07900)
Pfam (PF13589)
Homo sapiens (Human)Heat shock 86 kDa,HSP86,Lipopolysaccharide-associated protein 2,LPS-associated protein 2,Renal carcinoma antigen NY-REN-38
2B
(A)
(7S)-2-amino-4-methyl-7-phenyl-7,8-dihydroquinazolin-5(6H)-onenon-polymer253.31Chemie (3JC)
3C
(A)
waterwater18.0362Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26601.8
Non-Polymers*Number of molecules1
Total formula weight253.3
All*Total formula weight26855.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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