4W7P
Crystal Structure of ROCK 1 bound to YB-15-QD37
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Rho-associated protein kinase 1 | polymer | 411 | 47376.5 | 4 | UniProt (Q13464) Pfam (PF00069) In PDB | Homo sapiens (Human) | Renal carcinoma antigen NY-REN-35,Rho-associated,coiled-coil-containing protein kinase 1,coiled-coil-containing protein kinase I,ROCK-I,p160 ROCK-1,p160ROCK |
| 2 | A, B, C, D | N~1~-[2-(1H-indazol-5-yl)pyrido[3,4-d]pyrimidin-4-yl]-2-methylpropane-1,2-diamine | non-polymer | 333.4 | 4 | Chemie (3J7) | |||
| 3 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 2 - 410 (UniProt: Q13464)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| Ala 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 189506.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1333.6 | |
| All* | Total formula weight | 190839.6 |
