4W4X
JNK2/3 in complex with 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | c-jun NH2-terminal kinase 3 | polymer | 366 | 42261.9 | 1 | UniProt (P53779) Pfam (PF00069) In PDB | Homo sapiens (Human) | MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3, Mitogen-activated protein kinase 10 |
| 2 | A | 3-(4-{[(4-fluorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-N-(2-methylpyridin-4-yl)benzamide | non-polymer | 430.4 | 1 | Chemie (3HN) | |||
| 3 | water | water | 18.0 | 160 | Chemie (HOH) |
Sequence modifications
A: 39 - 402 (UniProt: P53779)
| PDB | External Database | Details |
|---|---|---|
| Met 37 | - | initiating methionine |
| Ala 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42261.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 430.4 | |
| All* | Total formula weight | 42692.4 |
