4W4L

Crystal structure of EspG5 in complex with PE25 and PPE41 from the ESX-5 type VII secretion system of M. tuberculosis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PE family protein PE25	polymer	109	11902.3	1	UniProt (H8ETC7)	Mycobacterium tuberculosis
2	B (B)	PPE family protein PPE41	polymer	174	19966.6	1	UniProt (H8ETC6)	Mycobacterium tuberculosis
3	C (C)	EspG5	polymer	314	33380.3	1	UniProt (H8F3E2)	Mycobacterium tuberculosis
4	D (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	E, F, G (A, B, C)	water	water		18.0	76	Chemie (HOH)

Sequence modifications

A: 1 - 99 (UniProt: H8ETC7)

PDB	External Database	Details
Ser 100	-	expression tag
Gly 101	-	expression tag
Glu 102	-	expression tag
Thr 103	-	expression tag
His 104	-	expression tag
His 105	-	expression tag
His 106	-	expression tag
His 107	-	expression tag
His 108	-	expression tag
His 109	-	expression tag

C: 1 - 300 (UniProt: H8F3E2)

PDB	External Database	Details
Ser 301	-	expression tag
Ser 302	-	expression tag
Gly 303	-	expression tag
Gly 304	-	expression tag
Gly 305	-	expression tag
Ser 306	-	expression tag
Gly 307	-	expression tag
Gly 308	-	expression tag
Gly 309	-	expression tag
Ser 310	-	expression tag
Gly 311	-	expression tag
Gly 312	-	expression tag
Gly 313	-	expression tag
Ser 314	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	65249.2
Non-Polymers*	Number of molecules	1
	Total formula weight	62.1
All*	Total formula weight	65311.3

*Water molecules are not included.