4W29
70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA, and tRNAs trapped in the AP/AP pe/E chimeric hybrid state.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, JB (AB, CB) | 30S ribosomal protein S2 | polymer | 235 | 27116.4 | 2 | UniProt (P62662) Pfam (PF00318) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 2 | B, KB (AC, CC) | 30S ribosomal protein S3 | polymer | 207 | 22975.6 | 2 | UniProt (P62663) Pfam (PF07650) Pfam (PF00189) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 3 | C, LB (AD, CD) | 30S ribosomal protein S4 | polymer | 208 | 24242.3 | 2 | UniProt (P62664) Pfam (PF00163) Pfam (PF01479) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 4 | D, MB (AE, CE) | 30S ribosomal protein S5 | polymer | 151 | 16460.2 | 2 | UniProt (P62665) Pfam (PF00333) Pfam (PF03719) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 5 | E, NB (AF, CF) | 30S ribosomal protein S6 | polymer | 101 | 11988.8 | 2 | UniProt (P62666) Pfam (PF01250) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 6 | F, OB (AG, CG) | 30S ribosomal protein S7 | polymer | 155 | 17919.8 | 2 | UniProt (P62667) Pfam (PF00177) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 7 | G, PB (AH, CH) | 30S ribosomal protein S8 | polymer | 138 | 15868.6 | 2 | UniProt (P62668) Pfam (PF00410) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 8 | H, QB (AI, CI) | 30S ribosomal protein S9 | polymer | 127 | 14279.4 | 2 | UniProt (P80374) Pfam (PF00380) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 9 | I, RB (AJ, CJ) | 30S ribosomal protein S10 | polymer | 99 | 11398.3 | 2 | UniProt (P62653) Pfam (PF00338) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 10 | J, SB (AK, CK) | 30S ribosomal protein S11 | polymer | 119 | 12606.4 | 2 | UniProt (P62654) Pfam (PF00411) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 11 | K, TB (AL, CL) | 30S ribosomal protein S12 | polymer | 125 | 13875.4 | 2 | UniProt (P61941) Pfam (PF00164) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 12 | L, UB (AM, CM) | 30S ribosomal protein S13 | polymer | 125 | 14207.7 | 2 | UniProt (P62655) Pfam (PF00416) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 13 | M, VB (AN, CN) | 30S ribosomal protein S14 type Z | polymer | 60 | 7027.5 | 2 | UniProt (P62656) Pfam (PF00253) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 14 | N, WB (AO, CO) | 30S ribosomal protein S15 | polymer | 88 | 10447.2 | 2 | UniProt (P62657) Pfam (PF00312) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 15 | O, XB (AP, CP) | 30S ribosomal protein S16 | polymer | 84 | 9995.5 | 2 | UniProt (P62238) Pfam (PF00886) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 16 | P, YB (AQ, CQ) | 30S ribosomal protein S17 | polymer | 100 | 11880.1 | 2 | UniProt (P0DOY7) Pfam (PF00366) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 17 | Q, ZB (AR, CR) | 30S ribosomal protein S18 | polymer | 70 | 8155.8 | 2 | UniProt (P62659) Pfam (PF01084) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 18 | AC, R (AS, CS) | 30S ribosomal protein S19 | polymer | 79 | 9006.5 | 2 | UniProt (P62660) Pfam (PF00203) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 19 | BC, S (AT, CT) | 30S ribosomal protein S20 | polymer | 99 | 10921.1 | 2 | UniProt (P80380) Pfam (PF01649) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 20 | CC, T (AY, CY) | Elongation factor G | polymer | 687 | 76510.5 | 2 | UniProt (Q72I01) Pfam (PF00009) Pfam (PF03144) Pfam (PF14492) Pfam (PF03764) Pfam (PF00679) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | EF-G |
| 21 | DC, U (AA, CA) | 16S Ribosomal RNA | polymer | 1511 | 490593.5 | 2 | GenBank (46197919) | Thermus thermophilus HB27 | |
| 22 | FC, V (AW, CW) | tRNA | polymer | 77 | 24728.7 | 2 | GenBank (1151176235) | Escherichia coli | |
| 23 | EC, W (AV, CV) | mRNA | polymer | 36 | 11747.2 | 2 | Escherichia coli str. K-12 | ||
| 24 | GC, X (AX, CX) | tRNA | polymer | 78 | 24608.7 | 2 | GenBank (1154835240) | Escherichia coli | |
| 25 | HC, Y (BC, DC) | 50S ribosomal protein L1 | polymer | 228 | 24741.5 | 2 | UniProt (A0A1J1EJ43) Pfam (PF00687) | Thermus thermophilus | |
| 26 | IC, Z (BD, DD) | 50S ribosomal protein L2 | polymer | 275 | 30401.4 | 2 | UniProt (Q72I07) Pfam (PF00181) Pfam (PF03947) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 27 | AA, JC (BE, DE) | 50S ribosomal protein L3 | polymer | 205 | 22321.0 | 2 | UniProt (Q72I04) Pfam (PF00297) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 28 | BA, KC (BF, DF) | 50S ribosomal protein L4 | polymer | 208 | 23071.7 | 2 | UniProt (Q5SHN9) Pfam (PF00573) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | L1e |
| 29 | CA, LC (BG, DG) | 50S ribosomal protein L5 | polymer | 181 | 20930.4 | 2 | UniProt (P41201) Pfam (PF00281) Pfam (PF00673) | Thermus thermophilus | TL4,TthL5 |
| 30 | DA, MC (BH, DH) | 50S ribosomal protein L6 | polymer | 167 | 18088.0 | 2 | UniProt (Q72I19) Pfam (PF00347) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 31 | EA, NC (BJ, DJ) | 50S ribosomal protein l10 | polymer | 170 | 14485.8 | 2 | Thermus thermophilus | ||
| 32 | FA, OC (BK, DK) | 50S ribosomal protein L11 | polymer | 140 | 14754.2 | 2 | UniProt (P62442) Pfam (PF03946) Pfam (PF00298) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 33 | GA, PC (BN, DN) | 50S ribosomal protein L13 | polymer | 139 | 15828.8 | 2 | UniProt (Q72IN1) Pfam (PF00572) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 34 | HA, QC (BO, DO) | 50S ribosomal protein L14 | polymer | 122 | 13323.6 | 2 | UniProt (A0A1J1EU54) Pfam (PF00238) | Thermus thermophilus | |
| 35 | IA, RC (BP, DP) | 50S ribosomal protein L15 | polymer | 146 | 15858.5 | 2 | UniProt (Q72I23) Pfam (PF00828) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 36 | JA, SC (BQ, DQ) | 50S ribosomal protein L16 | polymer | 141 | 15993.9 | 2 | UniProt (Q72I11) Pfam (PF00252) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 37 | KA, TC (BR, DR) | 50S ribosomal protein L17 | polymer | 117 | 13619.0 | 2 | UniProt (Q72I33) Pfam (PF01196) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 38 | LA, UC (BS, DS) | 50S ribosomal protein L18 | polymer | 99 | 10998.9 | 2 | UniProt (Q72I20) Pfam (PF00861) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 39 | MA, VC (BT, DT) | 50S ribosomal protein L19 | polymer | 138 | 16289.9 | 2 | UniProt (P60490) Pfam (PF01245) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 40 | NA, WC (BU, DU) | 50S ribosomal protein L20 | polymer | 117 | 13648.1 | 2 | UniProt (Q72L76) Pfam (PF00453) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 41 | OA, XC (BV, DV) | 50S ribosomal protein L21 | polymer | 101 | 11069.2 | 2 | UniProt (Q72HR2) Pfam (PF00829) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 42 | PA, YC (BW, DW) | 50S ribosomal protein L22 | polymer | 113 | 12808.1 | 2 | UniProt (Q72I09) Pfam (PF00237) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 43 | QA, ZC (BX, DX) | 50S ribosomal protein L23 | polymer | 93 | 10386.3 | 2 | UniProt (Q72I06) Pfam (PF00276) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 44 | AD, RA (BY, DY) | 50S ribosomal protein L24 | polymer | 107 | 11696.2 | 2 | UniProt (Q72I15) Pfam (PF00467) Pfam (PF17136) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 45 | BD, SA (BZ, DZ) | 50S ribosomal protein L25 | polymer | 185 | 20879.0 | 2 | UniProt (Q72IA7) Pfam (PF01386) Pfam (PF14693) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | General stress protein CTC |
| 46 | CD, TA (B0, D0) | 50S ribosomal protein L27 | polymer | 84 | 9397.9 | 2 | UniProt (P60493) Pfam (PF01016) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 47 | DD, UA (B1, D1) | 50S ribosomal protein L28 | polymer | 93 | 10430.4 | 2 | UniProt (P60494) Pfam (PF00830) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 48 | ED, VA (B2, D2) | 50S ribosomal protein L29 | polymer | 71 | 8539.1 | 2 | UniProt (Q72I12) Pfam (PF00831) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 49 | FD, WA (B3, D3) | 50S ribosomal protein L30 | polymer | 60 | 6799.1 | 2 | UniProt (Q72I22) Pfam (PF00327) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 50 | GD, XA (B4, D4) | 50S ribosomal protein L31 | polymer | 35 | 3893.6 | 2 | UniProt (Q72JR0) Pfam (PF01197) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 51 | HD, YA (B5, D5) | 50S ribosomal protein L32 | polymer | 59 | 6590.9 | 2 | UniProt (P80339) Pfam (PF01783) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 52 | ID, ZA (B6, D6) | 50S ribosomal protein L33 | polymer | 50 | 6214.4 | 2 | UniProt (Q72GW3) Pfam (PF00471) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 53 | AB, JD (B7, D7) | 50S ribosomal protein L34 | polymer | 49 | 6132.4 | 2 | UniProt (P80340) Pfam (PF00468) | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) | |
| 54 | BB, KD (B8, D8) | 50S ribosomal protein L35 | polymer | 64 | 7375.0 | 2 | UniProt (Q72L77) Pfam (PF01632) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 55 | CB, LD (B9, D9) | 50S ribosomal protein L36 | polymer | 37 | 4435.4 | 2 | UniProt (Q72I28) Pfam (PF00444) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 56 | DB, MD (Be, De) | 50S ribosomal protein L7/L12 | polymer | 103 | 10280.1 | 2 | UniProt (Q72GS2) Pfam (PF00542) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 57 | EB, FB, ND, OD (Bf, Bg, Df, Dg) | 50S ribosomal protein L7/L12 | polymer | 31 | 2656.3 | 4 | Thermus thermophilus | ||
| 58 | GB, PD (Bh, Dh) | 50S ribosomal protein L7/L12 | polymer | 30 | 2571.2 | 2 | Thermus thermophilus | ||
| 59 | HB, QD (BA, DA) | 23S Ribosomal RNA | polymer | 2879 | 936302.1 | 2 | GenBank (46197919) | Thermus thermophilus HB27 | |
| 60 | IB, RD (BB, DB) | 5S Ribosomal RNA | polymer | 119 | 38553.0 | 2 | GenBank (46197919) | Thermus thermophilus HB27 | |
| 61 | SD, ZD (AY, CY) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 2 | Chemie (GDP) | |||
| 62 | AE, TD (CY, AY) | FUSIDIC ACID | non-polymer | 516.7 | 2 | Chemie (FUA) | |||
| 63 | CE, DE, UD, WD, XD... (CA, DA, AA, BA) | NEOMYCIN | non-polymer | 614.6 | 6 | Chemie (NMY) | |||
| 64 | BE, VD (CY, BA) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
AY, CY: 4 - 690 (UniProt: Q72I01)
AX, CX: 1 - 76 (GenBank: 1154835240)
BQ, DQ: 1 - 141 (UniProt: Q72I11)
Be, De: 51 - 122 (UniProt: Q72GS2)
BA, DA: 6 - 2897 (GenBank: 46197919)
| PDB | External Database | Details |
|---|---|---|
| Thr 40 | His 40 | conflict |
| Lys 129 | His 129 | conflict |
| Asn 226 | His 226 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Val 77 | - | expression tag |
| Ace 78 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Tyr 32 | Phe 32 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Unk 1 | - | expression tag |
| Unk 2 | - | expression tag |
| Unk 3 | - | expression tag |
| Unk 4 | - | expression tag |
| Unk 5 | - | expression tag |
| Unk 6 | - | expression tag |
| Unk 7 | - | expression tag |
| Unk 8 | - | expression tag |
| Unk 9 | - | expression tag |
| Unk 10 | - | expression tag |
| Unk 11 | - | expression tag |
| Unk 12 | - | expression tag |
| Unk 13 | - | expression tag |
| Unk 14 | - | expression tag |
| Unk 15 | - | expression tag |
| Unk 16 | - | expression tag |
| Unk 17 | - | expression tag |
| Unk 18 | - | expression tag |
| Unk 19 | - | expression tag |
| Unk 20 | - | expression tag |
| Unk 21 | - | expression tag |
| Unk 22 | - | expression tag |
| Unk 23 | - | expression tag |
| Unk 24 | - | expression tag |
| Unk 25 | - | expression tag |
| Unk 26 | - | expression tag |
| Unk 27 | - | expression tag |
| Unk 28 | - | expression tag |
| Unk 29 | - | expression tag |
| Unk 30 | - | expression tag |
| Unk 31 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| U 1141 | C 1535654 | conflict |
| U 2825 | G 1537301 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 122 |
| Total formula weight | 4625163.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 5656.3 | |
| All* | Total formula weight | 4630819.5 |
