4W1W
Crystal structure of 7,8-diaminopelargonic acid synthase (BioA) from Mycobacterium tuberculosis, complexed with 7-(diethylamino)-3-(thiophene-2-carbonyl)-2H-chromen-2-one
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | polymer | 429 | 45708.4 | 2 | UniProt (P9WQ80) Pfam (PF00202) | Mycobacterium tuberculosis | 7,8-diamino-pelargonic acid aminotransferase,DAPA aminotransferase,8-diaminononanoate synthase,DANS,Diaminopelargonic acid synthase |
| 2 | C, J (A, B) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 2 | Chemie (PLP) | |||
| 3 | D, K (A, B) | 7-(diethylamino)-3-(thiophen-2-ylcarbonyl)-2H-chromen-2-one | non-polymer | 327.4 | 2 | Chemie (3G8) | |||
| 4 | E, F, G, H, I... (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 8 | Chemie (EDO) | |||
| 5 | L (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | P, Q (A, B) | water | water | 18.0 | 738 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91416.8 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1681.1 | |
| All* | Total formula weight | 93097.9 |
