4V9Q

Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	AA, CA	23S ribosomal RNA	polymer	2879	936302.1	2	GenBank (AE017221.1)	Thermus thermophilus
2	AB, CB	5S ribosomal RNA	polymer	119	38553.0	2	GenBank (AE017221.1)	Thermus thermophilus
3	AD, CD	50S ribosomal protein L2	polymer	271	29828.6	2	UniProt (Q72I07) Pfam (PF00181) Pfam (PF03947) In PDB	Thermus thermophilus
4	AE, CE	50S ribosomal protein L3	polymer	204	22250.0	2	UniProt (Q72I04) Pfam (PF00297) In PDB	Thermus thermophilus
5	AF, CF	50S ribosomal protein L4	polymer	202	22487.0	2	UniProt (Q72I05) Pfam (PF00573) In PDB	Thermus thermophilus
6	AG, CG	50S ribosomal protein L5	polymer	181	20944.4	2	UniProt (Q72I16) Pfam (PF00281) Pfam (PF00673) In PDB	Thermus thermophilus
7	AH, CH	50S ribosomal protein L6	polymer	159	17363.1	2	UniProt (Q72I19) Pfam (PF00347) In PDB	Thermus thermophilus
8	AI, CI	50S ribosomal protein L9	polymer	145	16107.9	2	UniProt (Q72GV5) Pfam (PF01281) Pfam (PF03948) In PDB	Thermus thermophilus
9	AJ, CJ	50S ribosomal protein L13	polymer	137	15568.5	2	UniProt (Q72IN1) Pfam (PF00572) In PDB	Thermus thermophilus
10	AK, CK	50S ribosomal protein L14	polymer	122	13309.6	2	UniProt (Q72I14) Pfam (PF00238) In PDB	Thermus thermophilus
11	AL, CL	50S ribosomal protein L15	polymer	146	15858.5	2	UniProt (Q72I23) Pfam (PF00828) In PDB	Thermus thermophilus
12	AM, CM	50S ribosomal protein L16	polymer	134	15148.8	2	UniProt (Q72I11) Pfam (PF00252) In PDB	Thermus thermophilus
13	AN, CN	50S ribosomal protein L17	polymer	117	13619.0	2	UniProt (Q72I33) Pfam (PF01196) In PDB	Thermus thermophilus
14	AO, CO	50S ribosomal protein L18	polymer	98	10941.9	2	UniProt (Q72I20) Pfam (PF00861) In PDB	Thermus thermophilus
15	AP, CP	50S ribosomal protein L19	polymer	137	16247.9	2	UniProt (Q72JU9) Pfam (PF01245) In PDB	Thermus thermophilus
16	AQ, CQ	50S ribosomal protein L20	polymer	117	13648.1	2	UniProt (Q72L76) Pfam (PF00453) In PDB	Thermus thermophilus
17	AR, CR	50S ribosomal protein L21	polymer	101	11069.2	2	UniProt (Q72HR2) Pfam (PF00829) In PDB	Thermus thermophilus
18	AS, CS	50S ribosomal protein L22	polymer	112	12678.9	2	UniProt (Q72I09) Pfam (PF00237) In PDB	Thermus thermophilus
19	AT, CT	50S ribosomal protein L23	polymer	92	10273.1	2	UniProt (Q72I06) Pfam (PF00276) In PDB	Thermus thermophilus
20	AU, CU	50S ribosomal protein L24	polymer	100	11078.5	2	UniProt (Q72I15) Pfam (PF00467) Pfam (PF17136) In PDB	Thermus thermophilus
21	AV, CV	50S ribosomal protein L25	polymer	187	21021.1	2	UniProt (Q72IA7) Pfam (PF01386) Pfam (PF14693) In PDB	Thermus thermophilus
22	AW, CW	50S ribosomal protein L27	polymer	76	8587.9	2	UniProt (Q72HR3) Pfam (PF01016) In PDB	Thermus thermophilus
23	AX, CX	50S ribosomal protein L28	polymer	88	9884.7	2	UniProt (Q72G84) Pfam (PF00830) In PDB	Thermus thermophilus
24	AY, CY	50S ribosomal protein L29	polymer	62	7457.9	2	UniProt (Q72I12) Pfam (PF00831) In PDB	Thermus thermophilus
25	AZ, CZ	50S ribosomal protein L30	polymer	59	6670.0	2	UniProt (Q72I22) Pfam (PF00327) In PDB	Thermus thermophilus
26	A1, C1	50S ribosomal protein L31	polymer	30	3278.9	2	UniProt (Q72JR0) Pfam (PF01197) In PDB	Thermus thermophilus
27	A2, C2	50S ribosomal protein L32	polymer	52	5818.9	2	UniProt (P62652) Pfam (PF01783) In PDB	Thermus thermophilus
28	A3, C3	50S ribosomal protein L33	polymer	44	5473.4	2	UniProt (Q72GW3) Pfam (PF00471) In PDB	Thermus thermophilus
29	A4, C4	50S ribosomal protein L34	polymer	48	5975.3	2	UniProt (P80340) Pfam (PF00468) In PDB	Thermus thermophilus
30	A5, C5	50S ribosomal protein L35	polymer	63	7245.9	2	UniProt (Q72L77) Pfam (PF01632) In PDB	Thermus thermophilus
31	BA, DA	16S ribosomal RNA	polymer	1504	488431.2	2	GenBank (AE017221.1)	Thermus thermophilus
32	BB, DB	30S ribosomal protein S2	polymer	234	26987.3	2	UniProt (P62662) Pfam (PF00318) In PDB	Thermus thermophilus
33	BC, DC	30S ribosomal protein S3	polymer	206	22862.4	2	UniProt (P62663) Pfam (PF07650) Pfam (PF00189) In PDB	Thermus thermophilus
34	BD, DD	30S ribosomal protein S4	polymer	208	24242.3	2	UniProt (P62664) Pfam (PF00163) Pfam (PF01479) In PDB	Thermus thermophilus
35	BE, DE	30S ribosomal protein S5	polymer	151	16460.2	2	UniProt (P62665) Pfam (PF00333) Pfam (PF03719) In PDB	Thermus thermophilus
36	BF, DF	30S ribosomal protein S6	polymer	101	11988.8	2	UniProt (P62666) Pfam (PF01250) In PDB	Thermus thermophilus
37	BG, DG	30S ribosomal protein S7	polymer	155	17919.8	2	UniProt (P62667) Pfam (PF00177) In PDB	Thermus thermophilus
38	BH, DH	30S ribosomal protein S8	polymer	138	15868.6	2	UniProt (P62668) Pfam (PF00410) In PDB	Thermus thermophilus
39	BI, DI	30S ribosomal protein S9	polymer	127	14298.5	2	UniProt (P62669) Pfam (PF00380) In PDB	Thermus thermophilus
40	BJ, DJ	30S ribosomal protein S10	polymer	98	11299.2	2	UniProt (P62653) Pfam (PF00338) In PDB	Thermus thermophilus
41	BK, DK	30S ribosomal protein S11	polymer	114	12014.7	2	UniProt (P62654) Pfam (PF00411) In PDB	Thermus thermophilus
42	BL, DL	30S ribosomal protein S12	polymer	122	13604.1	2	UniProt (P61941) Pfam (PF00164) In PDB	Thermus thermophilus
43	BM, DM	30S ribosomal protein S13	polymer	117	13308.5	2	UniProt (P62655) Pfam (PF00416) In PDB	Thermus thermophilus
44	BN, DN	30S ribosomal protein S14	polymer	60	7027.5	2	UniProt (P62656) Pfam (PF00253) In PDB	Thermus thermophilus
45	BO, DO	30S ribosomal protein S15	polymer	88	10447.2	2	UniProt (P62657) Pfam (PF00312) In PDB	Thermus thermophilus
46	BP, DP	30S ribosomal protein S16	polymer	83	9924.5	2	UniProt (P62238) Pfam (PF00886) In PDB	Thermus thermophilus
47	BQ, DQ	30S ribosomal protein S17	polymer	99	11721.9	2	UniProt (P62658) Pfam (PF00366) In PDB	Thermus thermophilus
48	BR, DR	30S ribosomal protein S18	polymer	70	8155.8	2	UniProt (P62659) Pfam (PF01084) In PDB	Thermus thermophilus
49	BS, DS	30S ribosomal protein S19	polymer	78	8949.4	2	UniProt (P62660) Pfam (PF00203) In PDB	Thermus thermophilus
50	BT, DT	30S ribosomal protein S20	polymer	99	10907.1	2	UniProt (P62661) Pfam (PF01649) In PDB	Thermus thermophilus
51	BU, DU	30S ribosomal protein Thx	polymer	24	2960.5	2	UniProt (P62613) Pfam (PF17070) In PDB	Thermus thermophilus
52	BV, BW, DV, DW	tRNA	polymer	77	24802.8	4		Escherichia coli
53	BX, DX	mRNA	polymer	5	1594.0	2		Synthetic DNA
54	AA, CA	BLASTICIDIN S	non-polymer		422.4	2	Chemie (BLS)
55	AA, BA, CA, DA, AB...	MAGNESIUM ION	non-polymer		24.3	4363	Chemie (MG)
56	DN, BD, DD, BN	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

AA, CA: 6 - 2897 (GenBank: AE017221.1)

PDB	External Database	Details
C 276	A 1534789	CONFLICT
A 277	C 1534790	CONFLICT
U 1142	C 1535654	CONFLICT
U 2825	G 1537301	CONFLICT

BM, DM: 2 - 117 (UniProt: P62655)

PDB	External Database	Details
Ala 118	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	108
	Total formula weight	4310541.9
Non-Polymers*	Number of molecules	4369
	Total formula weight	107149.2
All*	Total formula weight	4417691.2

*Water molecules are not included.