4V9Q

Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, CB (AA, CA)	23S ribosomal RNA	polymer	2879	936302.1	2	GenBank (AE017221.1)	Thermus thermophilus
2	B, DB (AB, CB)	5S ribosomal RNA	polymer	119	38553.0	2	GenBank (AE017221.1)	Thermus thermophilus
3	C, EB (AD, CD)	50S ribosomal protein L2	polymer	271	29828.6	2	UniProt (Q72I07) Pfam (PF00181) Pfam (PF03947)	Thermus thermophilus
4	D, FB (AE, CE)	50S ribosomal protein L3	polymer	204	22250.0	2	UniProt (Q72I04) Pfam (PF00297)	Thermus thermophilus
5	E, GB (AF, CF)	50S ribosomal protein L4	polymer	202	22487.0	2	UniProt (Q72I05) Pfam (PF00573)	Thermus thermophilus
6	F, HB (AG, CG)	50S ribosomal protein L5	polymer	181	20944.4	2	UniProt (Q72I16) Pfam (PF00281) Pfam (PF00673)	Thermus thermophilus
7	G, IB (AH, CH)	50S ribosomal protein L6	polymer	159	17363.1	2	UniProt (Q72I19) Pfam (PF00347)	Thermus thermophilus
8	H, JB (AI, CI)	50S ribosomal protein L9	polymer	145	16107.9	2	UniProt (Q72GV5) Pfam (PF01281) Pfam (PF03948)	Thermus thermophilus
9	I, KB (AJ, CJ)	50S ribosomal protein L13	polymer	137	15568.5	2	UniProt (Q72IN1) Pfam (PF00572)	Thermus thermophilus
10	J, LB (AK, CK)	50S ribosomal protein L14	polymer	122	13309.6	2	UniProt (Q72I14) Pfam (PF00238)	Thermus thermophilus
11	K, MB (AL, CL)	50S ribosomal protein L15	polymer	146	15858.5	2	UniProt (Q72I23) Pfam (PF00828)	Thermus thermophilus
12	L, NB (AM, CM)	50S ribosomal protein L16	polymer	134	15148.8	2	UniProt (Q72I11) Pfam (PF00252)	Thermus thermophilus
13	M, OB (AN, CN)	50S ribosomal protein L17	polymer	117	13619.0	2	UniProt (Q72I33) Pfam (PF01196)	Thermus thermophilus
14	N, PB (AO, CO)	50S ribosomal protein L18	polymer	98	10941.9	2	UniProt (Q72I20) Pfam (PF00861)	Thermus thermophilus
15	O, QB (AP, CP)	50S ribosomal protein L19	polymer	137	16247.9	2	UniProt (Q72JU9) Pfam (PF01245)	Thermus thermophilus
16	P, RB (AQ, CQ)	50S ribosomal protein L20	polymer	117	13648.1	2	UniProt (Q72L76) Pfam (PF00453)	Thermus thermophilus
17	Q, SB (AR, CR)	50S ribosomal protein L21	polymer	101	11069.2	2	UniProt (Q72HR2) Pfam (PF00829)	Thermus thermophilus
18	R, TB (AS, CS)	50S ribosomal protein L22	polymer	112	12678.9	2	UniProt (Q72I09) Pfam (PF00237)	Thermus thermophilus
19	S, UB (AT, CT)	50S ribosomal protein L23	polymer	92	10273.1	2	UniProt (Q72I06) Pfam (PF00276)	Thermus thermophilus
20	T, VB (AU, CU)	50S ribosomal protein L24	polymer	100	11078.5	2	UniProt (Q72I15) Pfam (PF00467) Pfam (PF17136)	Thermus thermophilus
21	U, WB (AV, CV)	50S ribosomal protein L25	polymer	187	21021.1	2	UniProt (Q72IA7) Pfam (PF01386) Pfam (PF14693)	Thermus thermophilus
22	V, XB (AW, CW)	50S ribosomal protein L27	polymer	76	8587.9	2	UniProt (Q72HR3) Pfam (PF01016)	Thermus thermophilus
23	W, YB (AX, CX)	50S ribosomal protein L28	polymer	88	9884.7	2	UniProt (Q72G84) Pfam (PF00830)	Thermus thermophilus
24	X, ZB (AY, CY)	50S ribosomal protein L29	polymer	62	7457.9	2	UniProt (Q72I12) Pfam (PF00831)	Thermus thermophilus
25	AC, Y (AZ, CZ)	50S ribosomal protein L30	polymer	59	6670.0	2	UniProt (Q72I22) Pfam (PF00327)	Thermus thermophilus
26	BC, Z (A1, C1)	50S ribosomal protein L31	polymer	30	3278.9	2	UniProt (Q72JR0) Pfam (PF01197)	Thermus thermophilus
27	AA, CC (A2, C2)	50S ribosomal protein L32	polymer	52	5818.9	2	UniProt (P62652) Pfam (PF01783)	Thermus thermophilus
28	BA, DC (A3, C3)	50S ribosomal protein L33	polymer	44	5473.4	2	UniProt (Q72GW3) Pfam (PF00471)	Thermus thermophilus
29	CA, EC (A4, C4)	50S ribosomal protein L34	polymer	48	5975.3	2	UniProt (P80340) Pfam (PF00468)	Thermus thermophilus
30	DA, FC (A5, C5)	50S ribosomal protein L35	polymer	63	7245.9	2	UniProt (Q72L77) Pfam (PF01632)	Thermus thermophilus
31	EA, GC (BA, DA)	16S ribosomal RNA	polymer	1504	488431.2	2	GenBank (AE017221.1)	Thermus thermophilus
32	FA, HC (BB, DB)	30S ribosomal protein S2	polymer	234	26987.3	2	UniProt (P62662) Pfam (PF00318)	Thermus thermophilus
33	GA, IC (BC, DC)	30S ribosomal protein S3	polymer	206	22862.4	2	UniProt (P62663) Pfam (PF07650) Pfam (PF00189)	Thermus thermophilus
34	HA, JC (BD, DD)	30S ribosomal protein S4	polymer	208	24242.3	2	UniProt (P62664) Pfam (PF00163) Pfam (PF01479)	Thermus thermophilus
35	IA, KC (BE, DE)	30S ribosomal protein S5	polymer	151	16460.2	2	UniProt (P62665) Pfam (PF00333) Pfam (PF03719)	Thermus thermophilus
36	JA, LC (BF, DF)	30S ribosomal protein S6	polymer	101	11988.8	2	UniProt (P62666) Pfam (PF01250)	Thermus thermophilus
37	KA, MC (BG, DG)	30S ribosomal protein S7	polymer	155	17919.8	2	UniProt (P62667) Pfam (PF00177)	Thermus thermophilus
38	LA, NC (BH, DH)	30S ribosomal protein S8	polymer	138	15868.6	2	UniProt (P62668) Pfam (PF00410)	Thermus thermophilus
39	MA, OC (BI, DI)	30S ribosomal protein S9	polymer	127	14298.5	2	UniProt (P62669) Pfam (PF00380)	Thermus thermophilus
40	NA, PC (BJ, DJ)	30S ribosomal protein S10	polymer	98	11299.2	2	UniProt (P62653) Pfam (PF00338)	Thermus thermophilus
41	OA, QC (BK, DK)	30S ribosomal protein S11	polymer	114	12014.7	2	UniProt (P62654) Pfam (PF00411)	Thermus thermophilus
42	PA, RC (BL, DL)	30S ribosomal protein S12	polymer	122	13604.1	2	UniProt (P61941) Pfam (PF00164)	Thermus thermophilus
43	QA, SC (BM, DM)	30S ribosomal protein S13	polymer	117	13308.5	2	UniProt (P62655) Pfam (PF00416)	Thermus thermophilus
44	RA, TC (BN, DN)	30S ribosomal protein S14	polymer	60	7027.5	2	UniProt (P62656) Pfam (PF00253)	Thermus thermophilus
45	SA, UC (BO, DO)	30S ribosomal protein S15	polymer	88	10447.2	2	UniProt (P62657) Pfam (PF00312)	Thermus thermophilus
46	TA, VC (BP, DP)	30S ribosomal protein S16	polymer	83	9924.5	2	UniProt (P62238) Pfam (PF00886)	Thermus thermophilus
47	UA, WC (BQ, DQ)	30S ribosomal protein S17	polymer	99	11721.9	2	UniProt (P62658) Pfam (PF00366)	Thermus thermophilus
48	VA, XC (BR, DR)	30S ribosomal protein S18	polymer	70	8155.8	2	UniProt (P62659) Pfam (PF01084)	Thermus thermophilus
49	WA, YC (BS, DS)	30S ribosomal protein S19	polymer	78	8949.4	2	UniProt (P62660) Pfam (PF00203)	Thermus thermophilus
50	XA, ZC (BT, DT)	30S ribosomal protein S20	polymer	99	10907.1	2	UniProt (P62661) Pfam (PF01649)	Thermus thermophilus
51	AD, YA (BU, DU)	30S ribosomal protein Thx	polymer	24	2960.5	2	UniProt (P62613) Pfam (PF17070)	Thermus thermophilus
52	AB, BD, CD, ZA (BV, BW, DV, DW)	tRNA	polymer	77	24802.8	4		Escherichia coli
53	BB, DD (BX, DX)	mRNA	polymer	5	1594.0	2		Synthetic DNA
54	ED, ZJE (AA, CA)	BLASTICIDIN S	non-polymer		422.4	2	Chemie (BLS)
55	AAA, AAB, AAC, AAD, AAE... (AA, BA, CA, DA, AB...)	MAGNESIUM ION	non-polymer		24.3	4363	Chemie (MG)
56	DNF, LBC, QMF, YBC (DN, BD, DD, BN)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)

Sequence modifications

AA, CA: 6 - 2897 (GenBank: AE017221.1)

PDB	External Database	Details
C 276	A 1534789	conflict
A 277	C 1534790	conflict
U 1142	C 1535654	conflict
U 2825	G 1537301	conflict

BM, DM: 2 - 117 (UniProt: P62655)

PDB	External Database	Details
Ala 118	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	108
	Total formula weight	4310541.9
Non-Polymers*	Number of molecules	4369
	Total formula weight	107149.2
All*	Total formula weight	4417691.2

*Water molecules are not included.