4V5Y

Crystal structure of the bacterial ribosome from Escherichia coli in complex with paromomycin and ribosome recycling factor (RRF).

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, BB (AA, CA)	16S rRNA	polymer	1542	499690.0	2	GenBank (83754040)	Escherichia coli
2	B, CB (AC, CC)	30S ribosomal protein S3	polymer	232	25900.1	2	UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189)	Escherichia coli
3	C, DB (AD, CD)	30S ribosomal protein S4	polymer	205	23383.0	2	UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479)	Escherichia coli
4	D, EB (AE, CE)	30S ribosomal protein S5	polymer	166	17498.2	2	UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719)	Escherichia coli
5	E, FB (AF, CF)	30S ribosomal protein S6	polymer	135	15727.5	2	UniProt (P02358) Pfam (PF01250)	Escherichia coli
6	F, GB (AG, CG)	30S ribosomal protein S7	polymer	178	19924.0	2	UniProt (P02359) Pfam (PF00177)	Escherichia coli
7	G, HB (AH, CH)	30S ribosomal protein S8	polymer	129	14015.4	2	UniProt (P0A7W7) Pfam (PF00410)	Escherichia coli
8	H, IB (AI, CI)	30S ribosomal protein S9	polymer	129	14755.1	2	UniProt (P0A7X3) Pfam (PF00380)	Escherichia coli
9	I, JB (AJ, CJ)	30S ribosomal protein S10	polymer	103	11755.6	2	UniProt (P0A7R5) Pfam (PF00338)	Escherichia coli
10	J, KB (AK, CK)	30S ribosomal protein S11	polymer	128	13739.8	2	UniProt (P0A7R9) Pfam (PF00411)	Escherichia coli
11	K, LB (AL, CL)	30S ribosomal protein S12	polymer	123	13637.0	2	UniProt (P0A7S3) Pfam (PF00164)	Escherichia coli
12	L, MB (AM, CM)	30S ribosomal protein S13	polymer	117	12997.3	2	UniProt (P0A7S9) Pfam (PF00416)	Escherichia coli
13	M, NB (AN, CN)	30S ribosomal protein S14	polymer	100	11475.4	2	UniProt (P0AG59) Pfam (PF00253)	Escherichia coli
14	N, OB (AO, CO)	30S ribosomal protein S15	polymer	89	10290.8	2	UniProt (P0ADZ4) Pfam (PF00312)	Escherichia coli
15	O, PB (AP, CP)	30S ribosomal protein S16	polymer	82	9207.6	2	UniProt (P0A7T3) Pfam (PF00886)	Escherichia coli
16	P, QB (AQ, CQ)	30S ribosomal protein S17	polymer	83	9593.3	2	UniProt (P0AG63) Pfam (PF00366)	Escherichia coli
17	Q, RB (AR, CR)	30S ribosomal protein S18	polymer	74	8874.3	2	UniProt (P0A7T7) Pfam (PF01084)	Escherichia coli
18	R, SB (AS, CS)	30S ribosomal protein S19	polymer	91	10324.2	2	UniProt (P0A7U3) Pfam (PF00203)	Escherichia coli
19	S, TB (AT, CT)	30S ribosomal protein S20	polymer	86	9577.3	2	UniProt (P0A7U7) Pfam (PF01649)	Escherichia coli
20	T, UB (AB, CB)	30S ribosomal protein S2	polymer	240	26650.5	2	UniProt (P0A7V0) Pfam (PF00318)	Escherichia coli
21	U, VB (AU, CU)	30S ribosomal protein S21	polymer	70	8392.8	2	UniProt (P68679) Pfam (PF01165)	Escherichia coli
22	V, WB (BA, DA)	5S rRNA	polymer	120	38790.1	2	GenBank (33357928)	Escherichia coli
23	W, XB (BB, DB)	23S rRNA	polymer	2904	941612.4	2	GenBank (33357927)	Escherichia coli
24	X, YB (BI, DI)	50S ribosomal protein L11	polymer	141	14763.2	2	UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298)	Escherichia coli
25	Y, ZB (BC, DC)	50S ribosomal protein L2	polymer	272	29792.4	2	UniProt (P60422) Pfam (PF00181) Pfam (PF03947)	Escherichia coli
26	AC, Z (BD, DD)	50S ribosomal protein L3	polymer	209	22277.5	2	UniProt (P60438) Pfam (PF00297)	Escherichia coli
27	AA, BC (BK, DK)	50S ribosomal protein L14	polymer	123	13565.1	2	UniProt (P0ADY3) Pfam (PF00238)	Escherichia coli
28	BA, CC (BP, DP)	50S ribosomal protein L19	polymer	114	13028.1	2	UniProt (P0A7K6) Pfam (PF01245)	Escherichia coli
29	CA, DC (BE, DE)	50S ribosomal protein L4	polymer	201	22121.6	2	UniProt (P60723) Pfam (PF00573)	Escherichia coli
30	DA, EC (BY, DY)	50S ribosomal protein L30	polymer	58	6423.6	2	UniProt (P0AG51) Pfam (PF00327)	Escherichia coli
31	EA, FC (B0, D0)	50S ribosomal protein L32	polymer	56	6332.2	2	UniProt (P0A7N4) Pfam (PF01783)	Escherichia coli
32	FA, GC (B4, D4)	50S ribosomal protein L36	polymer	38	4377.4	2	UniProt (P0A7Q6) Pfam (PF00444)	Escherichia coli	Ribosomal protein B
33	GA, HC (B1, D1)	50S ribosomal protein L33	polymer	54	6257.4	2	UniProt (P0A7N9) Pfam (PF00471)	Escherichia coli
34	HA, IC (B3, D3)	50S ribosomal protein L35	polymer	64	7181.8	2	UniProt (P0A7Q1) Pfam (PF01632)	Escherichia coli	Ribosomal protein A
35	IA, JC (BV, DV)	50S ribosomal protein L25	polymer	94	10713.5	2	UniProt (P68919) Pfam (PF01386)	Escherichia coli
36	JA, KC (B2, D2)	50S ribosomal protein L34	polymer	46	5397.5	2	UniProt (P0A7P5) Pfam (PF00468)	Escherichia coli
37	KA, LC (BL, DL)	50S ribosomal protein L15	polymer	144	15008.5	2	UniProt (P02413) Pfam (PF00828)	Escherichia coli
38	LA, MC (BM, DM)	50S ribosomal protein L16	polymer	136	15312.3	2	UniProt (P0ADY7) Pfam (PF00252)	Escherichia coli
39	MA, NC (BX, DX)	50S ribosomal protein L29	polymer	63	7286.5	2	UniProt (P0A7M6) Pfam (PF00831)	Escherichia coli
40	NA, OC (BH, DH)	50S ribosomal protein L9	polymer	149	15789.0	2	UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948)	Escherichia coli
41	OA, PC (BJ, DJ)	50S ribosomal protein L13	polymer	142	16050.6	2	UniProt (P0AA10) Pfam (PF00572)	Escherichia coli
42	PA, QC (BN, DN)	50S ribosomal protein L17	polymer	127	14393.7	2	UniProt (P0AG44) Pfam (PF01196)	Escherichia coli
43	QA, RC (BO, DO)	50S ribosomal protein L18	polymer	117	12794.7	2	UniProt (P0C018) Pfam (PF00861)	Escherichia coli
44	RA, SC (BQ, DQ)	50S ribosomal protein L20	polymer	117	13396.8	2	UniProt (P0A7L3) Pfam (PF00453)	Escherichia coli
45	SA, TC (BS, DS)	50S ribosomal protein L22	polymer	110	12253.4	2	UniProt (P61175) Pfam (PF00237)	Escherichia coli
46	TA, UC (BU, DU)	50S ribosomal protein L24	polymer	103	11208.1	2	UniProt (P60624) Pfam (PF00467) Pfam (PF17136)	Escherichia coli
47	UA, VC (BF, DF)	50S ribosomal protein L5	polymer	178	20202.4	2	UniProt (P62399) Pfam (PF00281) Pfam (PF00673)	Escherichia coli
48	VA, WC (BG, DG)	50S ribosomal protein L6	polymer	176	18801.6	2	UniProt (P0AG55) Pfam (PF00347)	Escherichia coli
49	WA, XC (BR, DR)	50S ribosomal protein L21	polymer	103	11586.4	2	UniProt (P0AG48) Pfam (PF00829)	Escherichia coli
50	XA, YC (BT, DT)	50S ribosomal protein L23	polymer	100	11222.2	2	UniProt (P0ADZ0) Pfam (PF00276)	Escherichia coli
51	YA, ZC (BZ, DZ)	50S ribosomal protein L28	polymer	78	9027.6	2	UniProt (P0A7M2) Pfam (PF00830)	Escherichia coli
52	AD, ZA (BW, DW)	50S ribosomal protein L27	polymer	84	9015.3	2	UniProt (P0A7L8) Pfam (PF01016)	Escherichia coli
53	AB, BD (B6, D6)	50S ribosomal protein RRF	polymer	185	21029.1	2	UniProt (Q9WX76) Pfam (PF01765)	Thermus thermophilus	Ribosome-releasing factor, RRF
54	AE, AF, AG, AH, AI... (AA, BB, CA, DB, CE)	MAGNESIUM ION	non-polymer		24.3	343	Chemie (MG)
55	CM, KF, LQ, RJ (CA, AA, DB, BB)	PAROMOMYCIN	non-polymer		615.6	4	Chemie (PAR)
56	MQ, SJ (D4, B4)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
57	AR, BR, CR, DR, ER... (CN, CP, CT, DB, DC...)	water	water		18.0	1627	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	106
	Total formula weight	4328841.2
Non-Polymers*	Number of molecules	349
	Total formula weight	10929.9
All*	Total formula weight	4339771.2

*Water molecules are not included.