4UZ7

STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM VI - 2.2A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	PROTEIN NOTUM HOMOLOG	polymer	383	43567.1	2	UniProt (Q6P988) Pfam (PF03283)	HOMO SAPIENS (HUMAN)
2	C (A)	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
3	D, E (A, B)	water	water		18.0	207	Chemie (HOH)

Sequence modifications

A, B: 81 - 451 (UniProt: Q6P988)

PDB	External Database	Details
Glu 78	-	expression tag
Thr 79	-	expression tag
Gly 80	-	expression tag
Gly 452	-	expression tag
Thr 453	-	expression tag
Lys 454	-	expression tag
His 455	-	expression tag
His 456	-	expression tag
His 457	-	expression tag
His 458	-	expression tag
His 459	-	expression tag
His 460	-	expression tag
Ser 330	Cys 330	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	87134.3
Non-Polymers*	Number of molecules	1
	Total formula weight	35.5
All*	Total formula weight	87169.7

*Water molecules are not included.