4UYW
STRUCTURE OF THE WNT DEACYLASE NOTUM - CRYSTAL FORM I HEPARIN FRAGMENT COMPLEX - 1.7A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | PROTEIN NOTUM HOMOLOG | polymer | 383 | 43567.1 | 2 | UniProt (Q6P988) Pfam (PF03283) In PDB | HOMO SAPIENS (HUMAN) | |
2 | C | 4-deoxy-2-O-sulfo-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose | branched | 577.5 | 1 | In PDB BIRD (PRD_900026) GlyTouCan (G01871HO) | HEPARIN DISACCHARIDE I-S, | ||
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
4 | water | water | 18.0 | 474 | Chemie (HOH) |
Sequence modifications
A, B: 81 - 451 (UniProt: Q6P988)
PDB | External Database | Details |
---|---|---|
Glu 78 | - | expression tag |
Thr 79 | - | expression tag |
Gly 80 | - | expression tag |
Gly 452 | - | expression tag |
Thr 453 | - | expression tag |
Lys 454 | - | expression tag |
His 455 | - | expression tag |
His 456 | - | expression tag |
His 457 | - | expression tag |
His 458 | - | expression tag |
His 459 | - | expression tag |
His 460 | - | expression tag |
Ser 330 | Cys 330 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 87134.3 | |
Branched | Number of molecules | 1 |
Total formula weight | 577.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 88154.2 |