4UXY
Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ALPHA TUBULIN | polymer | 451 | 50107.2 | 1 | UniProt (P81947) Pfam (PF00091) Pfam (PF03953) | BOS TAURUS (CATTLE) | |
| 2 | B (B) | BETA TUBULIN | polymer | 445 | 49907.8 | 1 | UniProt (Q6B856) Pfam (PF00091) Pfam (PF03953) | BOS TAURUS (CATTLE) | |
| 3 | C (C) | KINESIN-1 MOTOR DOMAIN | polymer | 340 | 38030.2 | 1 | UniProt (Q12840) Pfam (PF00225) | HOMO SAPIENS (HUMAN) | |
| 4 | D (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) PubChem (888) | |||
| 6 | F (A) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (135600366) PubChem (135749822) PubChem (136664747) PubChem (136803486) PubChem (164715984) PubChem (135398633) PubChem (135400627) PubChem (135487750) PubChem (135544356) PubChem (135547949) PubChem (136005188) PubChem (136073923) PubChem (136088935) PubChem (136240914) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (171699466) | |||
| 7 | G (B) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) PubChem (172898537) PubChem (135398619) PubChem (135402030) PubChem (135431654) PubChem (135566337) PubChem (135760556) PubChem (136026707) PubChem (136053418) PubChem (136073927) PubChem (136663964) PubChem (136664748) PubChem (136759848) PubChem (136759849) PubChem (136759850) PubChem (136836636) PubChem (136847074) | |||
| 8 | H (B) | TAXOL | non-polymer | 853.9 | 1 | Chemie (TA1) PubChem (101598423) PubChem (124747273) PubChem (126761000) PubChem (129395998) PubChem (46782671) PubChem (4666) PubChem (160585532) PubChem (36314) PubChem (60915) PubChem (163077211) PubChem (167423928) PubChem (177409) PubChem (184492) PubChem (441276) PubChem (118528174) PubChem (121459571) PubChem (5317123) PubChem (5321715) PubChem (5352019) PubChem (122361554) PubChem (124747271) PubChem (124747272) PubChem (124747274) PubChem (124893098) PubChem (6604028) PubChem (6604616) PubChem (6604814) PubChem (6713921) PubChem (6915727) PubChem (126968948) PubChem (129627423) PubChem (9875988) PubChem (132517454) PubChem (133052515) PubChem (133640187) PubChem (134368714) PubChem (134715514) PubChem (134972678) PubChem (10033513) PubChem (10485732) PubChem (10748131) PubChem (11320430) PubChem (11354895) PubChem (11506104) PubChem (11828953) PubChem (14060298) PubChem (14060299) PubChem (14060304) PubChem (14060306) PubChem (137705323) PubChem (138106885) PubChem (15983941) PubChem (16742549) PubChem (16757828) PubChem (16760177) PubChem (16760674) PubChem (21733096) PubChem (140512017) PubChem (140731501) PubChem (143890766) PubChem (144453087) PubChem (146034004) PubChem (23307219) PubChem (23307242) PubChem (23307253) PubChem (23307913) PubChem (23412627) PubChem (23636632) PubChem (24207713) PubChem (24754091) PubChem (24791027) PubChem (152743329) PubChem (153289350) PubChem (154037993) PubChem (154828192) PubChem (155982214) PubChem (24848897) PubChem (24867246) PubChem (25200067) PubChem (159121804) PubChem (159716711) PubChem (160053861) PubChem (160171678) PubChem (160585530) PubChem (42613129) PubChem (42620039) PubChem (44155032) PubChem (44276363) PubChem (44279927) PubChem (44291178) PubChem (44328863) PubChem (44335735) PubChem (44342632) PubChem (44356895) PubChem (44378736) PubChem (44403716) PubChem (45489039) PubChem (46781469) PubChem (57489669) PubChem (57908851) PubChem (57946364) PubChem (57999380) PubChem (58460861) PubChem (58596717) PubChem (58777027) PubChem (58798493) PubChem (58803237) PubChem (58877402) PubChem (49868078) PubChem (163077209) PubChem (163077210) PubChem (163077212) PubChem (163077213) PubChem (163077214) PubChem (163077215) PubChem (163284947) PubChem (53298534) PubChem (53313247) PubChem (165084161) PubChem (54259297) PubChem (54259298) PubChem (54259299) PubChem (166711459) PubChem (168322423) PubChem (169917882) PubChem (170014955) PubChem (59042813) PubChem (59048611) PubChem (170362150) PubChem (171036874) PubChem (5460441) PubChem (59844545) PubChem (59873251) PubChem (59904698) PubChem (59919147) PubChem (60005248) PubChem (60011010) PubChem (60123436) PubChem (60123443) PubChem (60147315) PubChem (66795656) PubChem (175758871) PubChem (70801836) PubChem (70842048) PubChem (70848451) PubChem (70856170) PubChem (70943371) PubChem (71096818) PubChem (71209844) PubChem (9854162) PubChem (9897470) PubChem (73707502) PubChem (73759704) PubChem (73759783) PubChem (89493063) PubChem (89847578) PubChem (90057663) PubChem (91122402) PubChem (14060309) PubChem (91885464) PubChem (21458255) PubChem (101920282) PubChem (44323108) PubChem (44356961) PubChem (59914794) PubChem (176586897) |
Sequence modifications
A: 0 - 424 (UniProt: P81947)
B: 0 - 444 (UniProt: Q6B856)
| PDB | External Database | Details |
|---|---|---|
| Ser 109 | Leu 136 | conflict |
| Gly 205 | Ser 232 | conflict |
| Gly 238 | Ile 265 | conflict |
| Thr 313 | Ser 340 | conflict |
| Glu 331 | Gln 358 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 54 | Thr 55 | conflict |
| Val 169 | Met 170 | conflict |
| Ala 295 | Ser 296 | conflict |
| Val 315 | Ile 316 | conflict |
| Gly 439 | Glu 440 | conflict |
| Glu 440 | Gly 441 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 138045.2 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1910.0 | |
| All* | Total formula weight | 139955.2 |
