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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

4UXO

Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)		TUBULIN ALPHA-1B CHAINpolymer45150107.21UniProt (P81947)
Pfam (PF00091)
Pfam (PF03953)		BOS TAURUS (CATTLE)ALPHA-TUBULIN UBIQUITOUS
2B
(B)		TUBULIN BETA-2B CHAINpolymer44549907.81UniProt (Q6B856)
Pfam (PF00091)
Pfam (PF03953)		BOS TAURUS (CATTLE)
3C
(C)		KINESIN-3 MOTOR DOMAINpolymer37542088.31UniProt (Q12756)
Pfam (PF00225)		Homo sapiens (Human)
4D
(A)		ZINC IONnon-polymer65.41Chemie (ZN)
5E
(A)		MAGNESIUM IONnon-polymer24.31Chemie (MG)
PubChem (888)
6F
(A)		GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
PubChem (177679032)
PubChem (135400627)
PubChem (135487750)
PubChem (136088935)
PubChem (136803486)
PubChem (135398633)
PubChem (135544356)
PubChem (135547949)
PubChem (135600366)
PubChem (135749822)
PubChem (136005188)
PubChem (136073923)
PubChem (136240914)
PubChem (136664747)
PubChem (136772743)
PubChem (136772744)
PubChem (136803487)
PubChem (137286749)
PubChem (164715984)
PubChem (171699466)
7G
(B)		GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
PubChem (136073927)
PubChem (135398619)
PubChem (135402030)
PubChem (135431654)
PubChem (135566337)
PubChem (135760556)
PubChem (136026707)
PubChem (136053418)
PubChem (136663964)
PubChem (136664748)
PubChem (136759848)
PubChem (136759849)
PubChem (136759850)
PubChem (136836636)
PubChem (136847074)
PubChem (172898537)
8H
(B)		TAXOLnon-polymer853.91Chemie (TA1)
PubChem (16757828)
PubChem (16760674)
PubChem (4666)
PubChem (21458255)
PubChem (23307219)
PubChem (23412627)
PubChem (23636632)
PubChem (16760177)
PubChem (16742549)
PubChem (24848897)
PubChem (24867246)
PubChem (21733096)
PubChem (23307242)
PubChem (23307253)
PubChem (23307913)
PubChem (44323108)
PubChem (44356961)
PubChem (44403716)
PubChem (24754091)
PubChem (24207713)
PubChem (24791027)
PubChem (25200067)
PubChem (42613129)
PubChem (42620039)
PubChem (44155032)
PubChem (44276363)
PubChem (46781469)
PubChem (44279927)
PubChem (44335735)
PubChem (44291178)
PubChem (44328863)
PubChem (44342632)
PubChem (44356895)
PubChem (44378736)
PubChem (49868078)
PubChem (45489039)
PubChem (46782671)
PubChem (54259298)
PubChem (71209844)
PubChem (57908851)
PubChem (57946364)
PubChem (58803237)
PubChem (53313247)
PubChem (53298534)
PubChem (54259297)
PubChem (59844545)
PubChem (54259299)
PubChem (59904698)
PubChem (60123443)
PubChem (57489669)
PubChem (57999380)
PubChem (58460861)
PubChem (58777027)
PubChem (58798493)
PubChem (58596717)
PubChem (59048611)
PubChem (59042813)
PubChem (58877402)
PubChem (60005248)
PubChem (59873251)
PubChem (59914794)
PubChem (59919147)
PubChem (60123436)
PubChem (60011010)
PubChem (60147315)
PubChem (66795656)
PubChem (70943371)
PubChem (71096818)
PubChem (5460441)
PubChem (14060298)
PubChem (176586897)
PubChem (177678861)
PubChem (73759783)
PubChem (36314)
PubChem (60915)
PubChem (177409)
PubChem (184492)
PubChem (70801836)
PubChem (70842048)
PubChem (70848451)
PubChem (70856170)
PubChem (441276)
PubChem (9854162)
PubChem (73707502)
PubChem (73759704)
PubChem (9897470)
PubChem (10033513)
PubChem (10485732)
PubChem (11506104)
PubChem (89493063)
PubChem (11828953)
PubChem (89847578)
PubChem (90057663)
PubChem (91122402)
PubChem (14060299)
PubChem (14060304)
PubChem (14060306)
PubChem (14060309)
PubChem (15983941)
PubChem (91885464)
PubChem (5317123)
PubChem (5321715)
PubChem (101920282)
PubChem (5352019)
PubChem (121459571)
PubChem (122361554)
PubChem (101598423)
PubChem (6604028)
PubChem (6604616)
PubChem (6604814)
PubChem (6713921)
PubChem (6915727)
PubChem (124747272)
PubChem (124893098)
PubChem (9875988)
PubChem (126968948)
PubChem (129395998)
PubChem (129627423)
PubChem (10748131)
PubChem (132517454)
PubChem (118528174)
PubChem (11320430)
PubChem (11354895)
PubChem (134368714)
PubChem (134972678)
PubChem (124747271)
PubChem (124747273)
PubChem (124747274)
PubChem (137705323)
PubChem (138106885)
PubChem (126761000)
PubChem (140731501)
PubChem (140512017)
PubChem (133052515)
PubChem (133640187)
PubChem (146034004)
PubChem (153289350)
PubChem (154037993)
PubChem (134715514)
PubChem (155982214)
PubChem (159121804)
PubChem (160053861)
PubChem (159716711)
PubChem (160171678)
PubChem (160585530)
PubChem (163077211)
PubChem (163077212)
PubChem (163077209)
PubChem (163284947)
PubChem (143890766)
PubChem (168322423)
PubChem (152743329)
PubChem (169917882)
PubChem (171036874)
PubChem (154828192)
PubChem (144453087)
PubChem (160585532)
PubChem (175758871)
PubChem (163077210)
PubChem (163077213)
PubChem (163077214)
PubChem (163077215)
PubChem (165084161)
PubChem (166711459)
PubChem (167423928)
PubChem (170014955)
PubChem (170362150)
Sequence modifications
A: 0 - 424 (UniProt: P81947)
PDBExternal DatabaseDetails
Ser 109Leu 136conflict
Gly 205Gly 232conflict
Gly 238Ile 265conflict
Thr 313Ser 340conflict
Glu 331Gln 358conflict
B: 0 - 444 (UniProt: Q6B856)
PDBExternal DatabaseDetails
Val 169Met 169conflict
Val 315Ile 315conflict
C: -5 - 361 (UniProt: Q12756)
PDBExternal DatabaseDetails
Ser -5-expression tag
Asp -4-expression tag
Asn -3-expression tag
Ala -2-expression tag
Ile -1-expression tag
Ala 0-expression tag
His 362-expression tag
His 363-expression tag
His 364-expression tag
His 365-expression tag
His 366-expression tag
His 367-expression tag
His 368-expression tag
His 369-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight142103.3
Non-Polymers*Number of molecules5
Total formula weight1910.0
All*Total formula weight144013.3
*Water molecules are not included.

251422

PDB entries from 2026-04-01

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