4UX6
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NITRIC OXIDE SYNTHASE, INDUCIBLE | polymer | 24 | 2797.1 | 1 | UniProt (P29477) | MUS MUSCULUS (HOUSE MOUSE) | INDUCIBLE NO SYNTHASE, INDUCIBLE NOS, INOS, MACROPHAGE NOS, MAC-NOS, NOS TYPE II, PEPTIDYL-CYSTEINE S-NITROSYLASE NOS2, INDUCIBLE NITRIC OXIDE SYNTHASE |
| 2 | B (B) | NITRIC OXIDE SYNTHASE, INDUCIBLE | polymer | 389 | 45035.2 | 1 | UniProt (P29477) Pfam (PF02898) | MUS MUSCULUS (HOUSE MOUSE) | INDUCIBLE NO SYNTHASE, INDUCIBLE NOS, INOS, MACROPHAGE NOS, MAC-NOS, NOS TYPE II, PEPTIDYL-CYSTEINE S-NITROSYLASE NOS2, INDUCIBLE NITRIC OXIDE SYNTHASE |
| 3 | C (B) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 4 | D (B) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 1 | Chemie (H4B) | |||
| 5 | E (B) | O-(5-methyl-2-nitrophenyl)-D-tyrosinamide | non-polymer | 315.3 | 1 | Chemie (YWO) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47832.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1173.1 | |
| All* | Total formula weight | 49005.4 |
