4UST
Crystal structure of human soluble Adenylyl Cyclase with pyrophosphate resulting from soaking with GTP and Magnesium
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADENYLATE CYCLASE TYPE 10 | polymer | 475 | 54269.7 | 1 | UniProt (Q96PN6) Pfam (PF00211) | HOMO SAPIENS (HUMAN) | AH-RELATED PROTEIN, ADENYLATE CYCLASE HOMOLOG, GERM CELL SO LUBLE ADENYLYL CYCLASE, HSAC, SAC, TESTICULAR SOLUBLE ADENYLYL CYC LASE, SOLUBLE ADENYLYL CYCLASE |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C, D (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | E (A) | PYROPHOSPHATE 2- | non-polymer | 176.0 | 1 | Chemie (POP) | |||
| 5 | F (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 6 | G, I (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | H (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | J (A) | water | water | 18.0 | 221 | Chemie (HOH) |
Sequence modifications
A: 1 - 469 (UniProt: Q96PN6)
| PDB | External Database | Details |
|---|---|---|
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54269.7 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 546.4 | |
| All* | Total formula weight | 54816.1 |
