4USK
Unravelling the B. pseudomallei heptokinase WcbL: from Structure to Drug Discovery.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | PUTATIVE SUGAR KINASE | polymer | 346 | 37847.3 | 2 | UniProt (H7C745) Pfam (PF00288) Pfam (PF08544) In PDB | BURKHOLDERIA PSEUDOMALLEI K96243 | WCBL, D-GLYCERO-BETA-D-MANNO-HEPTOSE-7-PHOSPHATE KINASE |
| 2 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 3 | A, B | CHLORIDE ION | non-polymer | 35.5 | 10 | Chemie (CL) | |||
| 4 | B | S-1,2-PROPANEDIOL | non-polymer | 76.1 | 1 | Chemie (PGO) | |||
| 5 | water | water | 18.0 | 845 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 346 (UniProt: H7C745)
| PDB | External Database | Details |
|---|---|---|
| Ala 179 | Glu 179 | engineered mutation |
| Ala 180 | Glu 180 | engineered mutation |
| Ala 181 | Glu 181 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75694.6 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 586.9 | |
| All* | Total formula weight | 76281.4 |
