4URA
Crystal structure of human JMJD2A in complex with compound 14a
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LYSINE-SPECIFIC DEMETHYLASE 4A | polymer | 360 | 41854.6 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, JUMONJI DOMAIN-CONTAINING PROTEIN 2A, JMJD2A |
| 2 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 3 | D, H (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | E, I (A, B) | NICKEL (II) ION | non-polymer | 58.7 | 2 | Chemie (NI) | |||
| 5 | F, J (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | G, K (A, B) | 2-(2H-1,2,3-triazol-4-yl)pyridine-4-carboxylic acid | non-polymer | 190.2 | 2 | Chemie (LEL) | |||
| 7 | L, M (A, B) | water | water | 18.0 | 185 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 359 (UniProt: O75164)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83709.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 882.7 | |
| All* | Total formula weight | 84591.9 |
