4UI1
Crystal structure of the human RGMC-BMP2 complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | BONE MORPHOGENETIC PROTEIN 2 | polymer | 114 | 12923.9 | 2 | UniProt (P12643) Pfam (PF00019) In PDB | HOMO SAPIENS (HUMAN) | BMP-2, BONE MORPHOGENETIC PROTEIN 2A, BMP-2A, BMP2 |
2 | C, D | HEMOJUVELIN | polymer | 122 | 12432.0 | 2 | UniProt (Q6ZVN8) Pfam (PF06535) In PDB | HOMO SAPIENS (HUMAN) | HEMOCHROMATOSIS TYPE 2 PROTEIN, RGM DOMAIN FAMILY MEMBER C, REPULSIVE GUIDANCE MOLECULE C, RGMC |
3 | A, B, D | NITRATE ION | non-polymer | 62.0 | 6 | Chemie (NO3) | |||
4 | A | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
5 | B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
6 | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
C, D: 35 - 145 (UniProt: Q6ZVN8)
PDB | External Database | Details |
---|---|---|
Glu 33 | - | expression tag |
Thr 34 | - | expression tag |
Gly 146 | - | expression tag |
Thr 147 | - | expression tag |
Lys 148 | - | expression tag |
His 149 | - | expression tag |
His 150 | - | expression tag |
His 151 | - | expression tag |
His 152 | - | expression tag |
His 153 | - | expression tag |
His 154 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 50711.7 | |
Non-Polymers* | Number of molecules | 11 |
Total formula weight | 629.1 | |
All* | Total formula weight | 51340.9 |