4UHR
Thermostabilised HUMAN A2a Receptor with CGS21680 bound
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THERMOSTABILISED HUMAN A2A RECEPTOR | polymer | 325 | 36022.8 | 1 | UniProt (P29274) Pfam (PF00001) | HOMO SAPIENS (HUMAN) | |
| 2 | B (A) | 2-[P-(2-CARBOXYETHYL)PHENYLETHYL-AMINO]-5'-N-ETHYLCARBOXAMIDO ADENOSINE | non-polymer | 499.5 | 1 | Chemie (NGI) | |||
| 3 | C (A) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 1 - 317 (UniProt: P29274)
| PDB | External Database | Details |
|---|---|---|
| Ala 318 | - | expression tag |
| Ala 319 | - | expression tag |
| Glu 320 | - | expression tag |
| Asn 321 | - | expression tag |
| Leu 322 | - | expression tag |
| Tyr 323 | - | expression tag |
| Phe 324 | - | expression tag |
| Gln 325 | - | expression tag |
| Ala 48 | Leu 48 | engineered mutation |
| Leu 54 | Ala 54 | engineered mutation |
| Ala 65 | Thr 65 | engineered mutation |
| Ala 89 | Gln 89 | engineered mutation |
| Ala 154 | Asn 154 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36022.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 499.5 | |
| All* | Total formula weight | 36522.3 |
