4UFK

Mouse Galactocerebrosidase complexed with dideoxy-imino-lyxitol DIL

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	GALACTOCEREBROSIDASE	polymer	654	74596.8	1	UniProt (P54818) Pfam (PF02057) Pfam (PF17387) Pfam (PF21708)	MUS MUSCULUS (HOUSE MOUSE)	GALCERASE, GALACTOCEREBROSIDE BETA-GALACTOSIDASE, GALACTOSYLCERAMIDASE, GALACTOSYLCERAMIDE BETA-GALACTOSIDASE
2	B, C (B, C)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
3	D (A)	DIDEOXY-IMINO-LYXITOL	non-polymer		133.1	1	Chemie (LDU) PubChem (1335) PubChem (24993934) PubChem (44306307) PubChem (127716) PubChem (56989959) PubChem (57107040) PubChem (57238164) PubChem (57246512) PubChem (59911470) PubChem (446222) PubChem (69922842) PubChem (451991) PubChem (452009) PubChem (68881456) PubChem (89423477) PubChem (90804485) PubChem (9877375) PubChem (9882222) PubChem (9898833) PubChem (9898834) PubChem (10953557) PubChem (70227439) PubChem (151369676) PubChem (163845957)
4	E, F, G (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)
5	H (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA) PubChem (271)
6	I (A)	water	water		18.0	181	Chemie (HOH)

Sequence modifications

A: 27 - 668 (UniProt: P54818)

PDB	External Database	Details
His 15	-	expression tag
His 16	-	expression tag
His 17	-	expression tag
His 18	-	expression tag
His 19	-	expression tag
His 20	-	expression tag
Ile 21	-	expression tag
Glu 22	-	expression tag
Gly 23	-	expression tag
Arg 24	-	expression tag
Gly 25	-	expression tag
Ala 26	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	74596.8
Branched	Number of molecules	2
	Total formula weight	848.8
Non-Polymers*	Number of molecules	5
	Total formula weight	836.8
All*	Total formula weight	76282.4

*Water molecules are not included.