4UDW
Thrombin in complex with 1-(2R)-2-amino-3-phenyl-propanoyl-N-(2, 5dichlorophenyl)methylpyrrolidine-2-carboxamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | THROMBIN HEAVY CHAIN | polymer | 258 | 29651.1 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2, THROMBIN ALPHA |
| 2 | B (I) | HIRUDIN VARIANT-2 | polymer | 11 | 1491.5 | 1 | UniProt (P09945) | HIRUDO MEDICINALIS | |
| 3 | C (L) | THROMBIN LIGHT CHAIN | polymer | 28 | 3317.7 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2, THROMBIN ALPHA |
| 4 | D, E (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 5 | F (H) | D-phenylalanyl-N-(2,5-dichlorobenzyl)-L-prolinamide | non-polymer | 420.3 | 1 | Chemie (N6L) | |||
| 6 | G (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 7 | H (H) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | I (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 9 | J, K, L (H, I, L) | water | water | 18.0 | 309 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34460.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 874.6 | |
| All* | Total formula weight | 35335.0 |
