4UDA
MR in complex with dexamethasone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MINERALOCORTICOID RECEPTOR | polymer | 251 | 29159.7 | 1 | UniProt (P08235) Pfam (PF00104) | HOMO SAPIENS (HUMAN) | MR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 2 |
| 2 | B (B) | NUCLEAR RECEPTOR COACTIVATOR 1 | polymer | 15 | 1726.0 | 1 | UniProt (Q15788) | HOMO SAPIENS (HUMAN) | NCOA-1, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 74, BHLHE74, PROTEIN HIN-2, RIP160, RENAL CARCINOMA ANTIGEN NY-REN-52, STEROID RECEPTOR COACTIVATOR 1, SRC-1, NCOA1 PEPTIDE |
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 4 | D (A) | DEXAMETHASONE | non-polymer | 392.5 | 1 | Chemie (DEX) PubChem (16757640) PubChem (21140858) PubChem (24758428) PubChem (24848023) PubChem (176476476) PubChem (176476477) PubChem (176481066) PubChem (176519880) PubChem (176541415) PubChem (18609236) PubChem (40467075) PubChem (45791747) PubChem (40467076) PubChem (40469527) PubChem (40469528) PubChem (40469529) PubChem (40469538) PubChem (40469540) PubChem (51654720) PubChem (68625576) PubChem (176476478) PubChem (46870667) PubChem (3036635) PubChem (9782) PubChem (155299) PubChem (71299643) PubChem (969487) PubChem (92043418) PubChem (92259599) PubChem (51529018) PubChem (51723203) PubChem (51723204) PubChem (5702012) PubChem (6432476) PubChem (6546942) PubChem (6604243) PubChem (6603742) PubChem (53316140) PubChem (124301806) PubChem (56627169) PubChem (57959704) PubChem (57959709) PubChem (59499751) PubChem (59553041) PubChem (60032782) PubChem (60107679) PubChem (60107685) PubChem (60113881) PubChem (60129028) PubChem (66739593) PubChem (67968282) PubChem (68163950) PubChem (68346426) PubChem (69301933) PubChem (70211292) PubChem (70834467) PubChem (70965822) PubChem (71083129) PubChem (73707402) PubChem (73945193) PubChem (73950719) PubChem (90141965) PubChem (92259552) PubChem (117072391) PubChem (3003) PubChem (5743) PubChem (123132537) PubChem (134645) PubChem (146915) PubChem (124190915) PubChem (124304345) PubChem (451600) PubChem (469455) PubChem (656865) PubChem (1150209) PubChem (1426961) PubChem (124904342) PubChem (124904343) PubChem (124918510) PubChem (124918511) PubChem (5702035) PubChem (6610297) PubChem (6610335) PubChem (6710614) PubChem (129010233) PubChem (9830630) PubChem (9865316) PubChem (11014684) PubChem (12358596) PubChem (12358597) PubChem (12358599) PubChem (12358600) PubChem (12358601) PubChem (12358603) PubChem (14697793) PubChem (133634290) PubChem (133645861) PubChem (134990893) PubChem (135396701) PubChem (137704752) PubChem (139404989) PubChem (140662068) PubChem (145705940) PubChem (146436354) PubChem (152964101) PubChem (162730335) PubChem (163285078) PubChem (163285103) PubChem (164010962) PubChem (175434953) PubChem (176282643) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 735 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Gly 734 | - | expression tag |
| Ser 808 | Cys 808 | engineered mutation |
| Ser 910 | Cys 910 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30885.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 484.6 | |
| All* | Total formula weight | 31370.2 |
