4UDA
MR in complex with dexamethasone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | MINERALOCORTICOID RECEPTOR | polymer | 251 | 29159.7 | 1 | UniProt (P08235) Pfam (PF00104) | HOMO SAPIENS (HUMAN) | MR, NUCLEAR RECEPTOR SUBFAMILY 3 GROUP C MEMBER 2 |
| 2 | B (B) | NUCLEAR RECEPTOR COACTIVATOR 1 | polymer | 15 | 1726.0 | 1 | UniProt (Q15788) | HOMO SAPIENS (HUMAN) | NCOA-1, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 74, BHLHE74, PROTEIN HIN-2, RIP160, RENAL CARCINOMA ANTIGEN NY-REN-52, STEROID RECEPTOR COACTIVATOR 1, SRC-1, NCOA1 PEPTIDE |
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | DEXAMETHASONE | non-polymer | 392.5 | 1 | Chemie (DEX) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 101 | Chemie (HOH) |
Sequence modifications
A: 735 - 984 (UniProt: P08235)
| PDB | External Database | Details |
|---|---|---|
| Gly 734 | - | expression tag |
| Ser 808 | Cys 808 | engineered mutation |
| Ser 910 | Cys 910 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30885.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 484.6 | |
| All* | Total formula weight | 31370.2 |
