4UD7
Structure of the stapled peptide YS-02 bound to MDM2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D | MDM2 | polymer | 114 | 12830.7 | 4 | UniProt (Q00987) Pfam (PF02201) In PDB | HOMO SAPIENS (HUMAN) | |
2 | F, G, H, I | YS-02 | polymer | 16 | 1840.1 | 4 | SYNTHETIC CONSTRUCT | ||
3 | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 17 - 125 (UniProt: Q00987)
PDB | External Database | Details |
---|---|---|
Gly 12 | - | expression tag |
Pro 13 | - | expression tag |
Leu 14 | - | expression tag |
Gly 15 | - | expression tag |
Ser 16 | - | expression tag |
Ala 69 | Glu 69 | engineered mutation |
Ala 70 | Lys 70 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 58683.1 | |
All* | Total formula weight | 58683.1 |