4UD0

X-ray structure and activities of an essential Mononegavirales L- protein domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (B)	RNA-DIRECTED RNA POLYMERASE L	polymer	415	47629.1	1	UniProt (Q91L20)	HUMAN METAPNEUMOVIRUS	LARGE STRUCTURAL PROTEIN
2	B (B)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
3	C (B)	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
4	D (B)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (13792) PubChem (177678424) PubChem (189149) PubChem (439155) PubChem (25210495) PubChem (21125603) PubChem (44361184) PubChem (25203782) PubChem (46936206) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (57544532) PubChem (52224400) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (5284331) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (71170554) PubChem (13231890) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (164157219) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
5	E (B)	water	water		18.0	20	Chemie (HOH)

Sequence modifications

B: 1600 - 2005 (UniProt: Q91L20)

PDB	External Database	Details
Met 1599	-	expression tag
Ala 1877	Cys 1877	engineered mutation
Ser 2006	-	expression tag
Gly 2007	-	expression tag
His 2008	-	expression tag
His 2009	-	expression tag
His 2010	-	expression tag
His 2011	-	expression tag
His 2012	-	expression tag
His 2013	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	47629.1
Non-Polymers*	Number of molecules	3
	Total formula weight	545.9
All*	Total formula weight	48175.0

*Water molecules are not included.