4UCI

X-ray structure and activities of an essential Mononegavirales L- protein domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	RNA-DIRECTED RNA POLYMERASE L	polymer	415	47661.2	2	UniProt (Q6WB93) Pfam (PF14314) UniProt (by SIFTS) (Q91L20) In PDB	HUMAN METAPNEUMOVIRUS	LARGE STRUCTURAL PROTEIN
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A, B	S-ADENOSYLMETHIONINE	non-polymer		398.4	2	Chemie (SAM)
4	A, B	GUANOSINE-5'-TRIPHOSPHATE	non-polymer		523.2	2	Chemie (GTP)
5	A, B	GLYCEROL	non-polymer		92.1	7	Chemie (GOL)
6	A, B	ADENOSINE	non-polymer		267.2	2	Chemie (ADN)
7		water	water		18.0	382	Chemie (HOH)

Sequence modifications

A, B: 1600 - 2005 (UniProt: Q6WB93)

PDB	External Database	Details
Met 1599	-	expression tag
Ser 2006	-	expression tag
Gly 2007	-	expression tag
His 2008	-	expression tag
His 2009	-	expression tag
His 2010	-	expression tag
His 2011	-	expression tag
His 2012	-	expression tag
His 2013	-	expression tag
Pro 1606	Ser 1606	conflict
Glu 1620	Thr 1620	conflict
Asn 1860	Ser 1860	conflict
Asn 1912	Asp 1912	conflict
Val 1935	Ile 1935	conflict
Asn 1946	Ser 1946	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	95322.3
Non-Polymers*	Number of molecules	15
	Total formula weight	3153.2
All*	Total formula weight	98475.5

*Water molecules are not included.