4U7Z
Mitogen-Activated Protein Kinase Kinase (MEK1) bound to G805
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Dual specificity mitogen-activated protein kinase kinase 1 | polymer | 341 | 37929.6 | 1 | UniProt (Q02750) Pfam (PF00069) In PDB | Homo sapiens (Human) | MKK1,ERK activator kinase 1,MAPK/ERK kinase 1,MEK 1 |
| 2 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | A | 5-[(4-bromo-2-chlorophenyl)amino]-4-fluoro-N-(2-hydroxyethoxy)-1-methyl-1H-benzimidazole-6-carboxamide | non-polymer | 457.7 | 1 | Chemie (3EW) | |||
| 4 | A | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | water | water | 18.0 | 11 | Chemie (HOH) |
Sequence modifications
A: 62 - 393 (UniProt: Q02750)
| PDB | External Database | Details |
|---|---|---|
| Met 61 | - | initiating methionine |
| Leu 394 | - | expression tag |
| Gln 395 | - | expression tag |
| His 396 | - | expression tag |
| His 397 | - | expression tag |
| His 398 | - | expression tag |
| His 399 | - | expression tag |
| His 400 | - | expression tag |
| His 401 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37929.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 988.2 | |
| All* | Total formula weight | 38917.8 |
