4U7Q
Structure of wild-type HIV protease in complex with photosensitive inhibitor PDI-6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | V-1 protease | polymer | 99 | 10804.8 | 2 | UniProt (Q9Q2G4) Pfam (PF00077) UniProt (by SIFTS) (P04585) | Human immunodeficiency virus 1 | |
| 2 | C (B) | N~2~-({[7-(diethylamino)-2-oxo-2H-chromen-4-yl]methoxy}carbonyl)-N-[(2S,4S,5S)-4-hydroxy-1,6-diphenyl-5-{[(1,3-thiazol-5-ylmethoxy)carbonyl]amino}hexan-2-yl]-L-valinamide | non-polymer | 798.0 | 1 | Chemie (3EM) | |||
| 3 | D, E (A, B) | water | water | 18.0 | 90 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q9Q2G4)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | conflict |
| Ile 33 | Leu 33 | conflict |
| Ser 37 | Asn 37 | conflict |
| Ile 63 | Leu 63 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21609.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 798.0 | |
| All* | Total formula weight | 22407.6 |
