4U79
Crystal structure of human JNK3 in complex with a benzenesulfonamide inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 10 | polymer | 364 | 42059.7 | 1 | UniProt (P53779) Pfam (PF00069) | Homo sapiens (Human) | MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3 |
| 2 | B (A) | N-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]naphthalen-1-yl}benzenesulfonamide | non-polymer | 566.7 | 1 | Chemie (3EL) | |||
| 3 | C (A) | water | water | 18.0 | 33 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42059.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 566.7 | |
| All* | Total formula weight | 42626.3 |
