4U79

Crystal structure of human JNK3 in complex with a benzenesulfonamide inhibitor.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Mitogen-activated protein kinase 10	polymer	364	42059.7	1	UniProt (P53779) Pfam (PF00069) In PDB	Homo sapiens (Human)	MAPK 10,MAP kinase p49 3F12,Stress-activated protein kinase 1b,SAPK1b,Stress-activated protein kinase JNK3,c-Jun N-terminal kinase 3
2	A	N-{4-[(3-{2-[(trans-4-aminocyclohexyl)amino]pyrimidin-4-yl}pyridin-2-yl)oxy]naphthalen-1-yl}benzenesulfonamide	non-polymer		566.7	1	Chemie (3EL)
3		water	water		18.0	33	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42059.7
Non-Polymers*	Number of molecules	1
	Total formula weight	566.7
All*	Total formula weight	42626.3

*Water molecules are not included.