4U74
Crystal structure of 4-phenylimidazole bound form of human indoleamine 2,3-dioxygenase (G262A mutant)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Indoleamine 2,3-dioxygenase 1 | polymer | 406 | 45680.5 | 2 | UniProt (P14902) Pfam (PF01231) In PDB | Homo sapiens (Human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | A, B | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 2 | Chemie (HEM) | |||
| 3 | A, B | 4-PHENYL-1H-IMIDAZOLE | non-polymer | 144.2 | 2 | Chemie (PIM) | |||
| 4 | A, B | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID | non-polymer | 207.3 | 4 | Chemie (NHE) | |||
| 5 | water | water | 18.0 | 307 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 403 (UniProt: P14902)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Ala 262 | Gly 262 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 91361.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 2350.5 | |
| All* | Total formula weight | 93711.5 |
