4U4L
Crystal structure of the metallo-beta-lactamase NDM-1 in complex with a bisthiazolidine inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Beta-lactamase NDM-1 | polymer | 246 | 26014.3 | 4 | UniProt (C7C422) Pfam (PF00753) | Klebsiella pneumoniae | NDM-1,Metallo-beta-lactamase NDM-1 |
| 2 | E, F, H, I, K... (A, B, C, D) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 3 | G, J, N, R (A, B, C, D) | (3R,5R,7aS)-5-(sulfanylmethyl)tetrahydro[1,3]thiazolo[4,3-b][1,3]thiazole-3-carboxylic acid | non-polymer | 237.4 | 4 | Chemie (3C7) | |||
| 4 | M, Q (C, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 624 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 27 - 270 (UniProt: C7C422)
| PDB | External Database | Details |
|---|---|---|
| Gly 25 | - | expression tag |
| Pro 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 104057.2 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1656.9 | |
| All* | Total formula weight | 105714.1 |
