4U4F

Structure of GluA2* in complex with partial agonist (S)-5-Nitrowillardiine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	Glutamate receptor 2	polymer	822	92238.3	4	UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) In PDB	Rattus norvegicus (Rat)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2
2	E, F, G	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
3	A, B, C, D	3-(5-nitro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-L-alanine	non-polymer		244.2	4	Chemie (NWD)
4	D	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	1	Chemie (NAG)

Sequence modifications

A, B, C, D: 10 - 826 (UniProt: P19491)

PDB	External Database	Details
Glu 241	Asn 256	conflict
Leu 382	Val 397	conflict
-	Leu 399	deletion
-	Thr 400	deletion
-	Glu 401	deletion
-	Leu 402	deletion
-	Pro 403	deletion
-	Ser 404	deletion
Glu 384	Gly 405	conflict
Asp 385	Asn 406	conflict
Gln 392	Asn 413	conflict
Gly 827	-	expression tag
Leu 828	-	expression tag
Val 829	-	expression tag
Pro 830	-	expression tag
Arg 831	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	368953.3
Branched	Number of molecules	3
	Total formula weight	1273.2
Non-Polymers*	Number of molecules	5
	Total formula weight	1197.9
All*	Total formula weight	371424.3

*Water molecules are not included.