4U44
MAP4K4 in complex with inhibitor (compound 16)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Mitogen-activated protein kinase kinase kinase kinase 4 | polymer | 332 | 37870.1 | 2 | UniProt (O95819) Pfam (PF00069) In PDB | Homo sapiens (Human) | HPK/GCK-like kinase HGK,MAPK/ERK kinase kinase kinase 4,MEKKK 4,Nck-interacting kinase |
2 | A | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
3 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
4 | A | 6-phenyl-N-(pyridin-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | non-polymer | 287.3 | 1 | Chemie (3D9) | |||
5 | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 328 (UniProt: O95819)
PDB | External Database | Details |
---|---|---|
Gly 0 | - | expression tag |
Ser 1 | - | expression tag |
Gly 329 | - | expression tag |
Asn 330 | - | expression tag |
Ser 331 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75740.2 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 505.5 | |
All* | Total formula weight | 76245.7 |