4U32
Human mesotrypsin complexed with HAI-2 Kunitz domain 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | X | Kunitz-type protease inhibitor 2 | polymer | 55 | 6304.2 | 1 | UniProt (O43291) Pfam (PF00014) In PDB | Homo sapiens (Human) | Hepatocyte growth factor activator inhibitor type 2,HAI-2,Placental bikunin |
| 2 | A | Trypsin-3 | polymer | 224 | 24257.5 | 1 | UniProt (P35030) Pfam (PF00089) In PDB | Homo sapiens (Human) | Brain trypsinogen,Mesotrypsinogen,Serine protease 3,Serine protease 4,Trypsin III,Trypsin IV |
| 3 | X | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 4 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | water | water | 18.0 | 222 | Chemie (HOH) |
Sequence modifications
A: 16 - 246 (UniProt: P35030)
| PDB | External Database | Details |
|---|---|---|
| Ala 127 | Thr 188 | variant |
| Ala 195 | Ser 257 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30561.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 261.3 | |
| All* | Total formula weight | 30823.0 |
