4U2Q
Full-length AMPA subtype ionotropic glutamate receptor GluA2 in complex with partial agonist kainate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glutamate receptor 2 | polymer | 824 | 92386.4 | 4 | UniProt (P19491) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Rat) | GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2 |
| 2 | E, G, I, K (A, B, C, D) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 4 | Chemie (KAI) | |||
| 3 | F, H, J (A, B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) |
Sequence modifications
A, B, C, D: 8 - 826 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Glu 239 | Asn 256 | conflict |
| - | Leu 402 | deletion |
| - | Pro 403 | deletion |
| - | Ser 404 | deletion |
| - | Gly 405 | deletion |
| Asp 385 | Asn 406 | conflict |
| Gln 392 | Asn 413 | conflict |
| Ala 528 | Cys 549 | conflict |
| Phe 585 | Met 606 | conflict |
| Ala 589 | Cys 610 | conflict |
| Ala 598 | Gly 619 | conflict |
| Ala 602 | Gly 623 | conflict |
| Ala 815 | Cys 836 | conflict |
| Gly 827 | - | expression tag |
| Leu 828 | - | expression tag |
| Val 829 | - | expression tag |
| Pro 830 | - | expression tag |
| Arg 831 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 369545.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1516.5 | |
| All* | Total formula weight | 371062.1 |
