4U1S
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HLA class I histocompatibility antigen, B-81 alpha chain | polymer | 278 | 32145.3 | 1 | UniProt (Q31610) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) In PDB | Homo sapiens (Human) | B'DT,MHC class I antigen B*81 |
| 2 | B | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) In PDB | Homo sapiens (Human) | |
| 3 | C | Vpr protein | polymer | 9 | 1124.3 | 1 | UniProt (T2D0U8) UniProt (by SIFTS) (P69726) In PDB | Human immunodeficiency virus 1 | FL9 |
| 4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
| 5 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 1 - 277 (UniProt: Q31610)
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45149.0 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 933.0 | |
| All* | Total formula weight | 46082.0 |
