4U1Q

Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in complex with 3HK and SAH

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	SibL	polymer	355	38923.8	4	UniProt (C0LTM6)	Streptosporangium sibiricum
2	E, G, I, K (A, B, C, D)	(2S)-2-amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid	non-polymer		224.2	4	Chemie (3DJ) PubChem (11811) PubChem (6604307) PubChem (89)
3	F, H, J, L (A, B, C, D)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	4	Chemie (SAH) PubChem (193) PubChem (13792) PubChem (189149) PubChem (439155) PubChem (5284331) PubChem (71170554) PubChem (13231890) PubChem (16760024) PubChem (25210495) PubChem (44361184) PubChem (177678424) PubChem (46936206) PubChem (21125603) PubChem (25203782) PubChem (52224400) PubChem (50989525) PubChem (51380914) PubChem (52224398) PubChem (6419189) PubChem (57544532) PubChem (59046843) PubChem (59170628) PubChem (164157219) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (118374891) PubChem (118560068) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	M, N, O, P (A, B, C, D)	water	water		18.0	995	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 344 (UniProt: C0LTM6)

PDB	External Database	Details
Ala 345	-	expression tag
Ala 346	-	expression tag
Ala 347	-	expression tag
Leu 348	-	expression tag
Glu 349	-	expression tag
His 350	-	expression tag
His 351	-	expression tag
His 352	-	expression tag
His 353	-	expression tag
His 354	-	expression tag
His 355	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	155695.2
Non-Polymers*	Number of molecules	8
	Total formula weight	2434.5
All*	Total formula weight	158129.7

*Water molecules are not included.