4U1P

Human Fyn-SH2 domain in complex with a synthetic high-affinity phospho-peptide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Tyrosine-protein kinase Fyn	polymer	122	14122.0	1	UniProt (P06241) Pfam (PF00017) In PDB	Homo sapiens (Human)	Proto-oncogene Syn,Proto-oncogene c-Fyn,Src-like kinase,SLK,p59-Fyn
2	B	Middle T antigen	polymer	11	1473.5	1	UniProt (K0F5T5) UniProt (by SIFTS) (P03079) In PDB	Hamster polyomavirus
3	A	POLYETHYLENE GLYCOL (N=34)	non-polymer		1529.8	1	Chemie (15P)
4	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
5		water	water		18.0	185	Chemie (HOH)

Sequence modifications

A: 22 - 122 (UniProt: P06241)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ser 3	-	expression tag
Ser 4	-	expression tag
His 5	-	expression tag
His 6	-	expression tag
His 7	-	expression tag
His 8	-	expression tag
His 9	-	expression tag
His 10	-	expression tag
Ser 11	-	expression tag
Ser 12	-	expression tag
Gly 13	-	expression tag
Leu 14	-	expression tag
Val 15	-	expression tag
Pro 16	-	expression tag
Arg 17	-	expression tag
Gly 18	-	expression tag
Ser 19	-	expression tag
His 20	-	expression tag
Met 21	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	15595.5
Non-Polymers*	Number of molecules	2
	Total formula weight	1552.8
All*	Total formula weight	17148.3

*Water molecules are not included.