4U1K

HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	HLA class I histocompatibility antigen, B-7 alpha chain	polymer	277	32190.3	2	UniProt (P01889) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (Human)	MHC class I antigen B*7
2	B, E	Beta-2-microglobulin	polymer	100	11879.4	2	UniProt (P61769) Pfam (PF07654) In PDB	Homo sapiens (Human)
3	C, F	Protein Nef	polymer	9	1095.4	2	UniProt (Q90VG9) UniProt (by SIFTS) (P03407) In PDB	Human immunodeficiency virus 1	RM9
4	A, D	GLYCEROL	non-polymer		92.1	8	Chemie (GOL)
5	A, D	1,2-ETHANEDIOL	non-polymer		62.1	6	Chemie (EDO)
6	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
7		water	water		18.0	497	Chemie (HOH)

Sequence modifications

A, D: 1 - 276 (UniProt: P01889)

PDB	External Database	Details
Met 0	-	initiating methionine

B, E: 1 - 99 (UniProt: P61769)

PDB	External Database	Details
Met 0	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	90330.1
Non-Polymers*	Number of molecules	15
	Total formula weight	1205.2
All*	Total formula weight	91535.3

*Water molecules are not included.