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4U1J

HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HLA class I histocompatibility antigen, B-42 alpha chainpolymer27832148.21UniProt (P30480)
Pfam (PF00129)
Pfam (PF07654)
UniProt (by SIFTS) (P01889)
Homo sapiens (Human)MHC class I antigen B*42
2B
(B)
Beta-2-microglobulinpolymer10011879.41UniProt (P61769)
Pfam (PF07654)
Homo sapiens (Human)
3C
(C)
GAG proteinpolymer91032.21UniProt (Q70A36)
UniProt (by SIFTS) (P04585)
Human immunodeficiency virus 1TL9
4D, E, F, G, H...
(A, B)
1,2-ETHANEDIOLnon-polymer62.17Chemie (EDO)
5K, L, M
(A, B, C)
waterwater18.0419Chemie (HOH)
Sequence modifications
A: 1 - 277 (UniProt: P30480)
PDBExternal DatabaseDetails
Met 0-initiating methionine
B: 1 - 99 (UniProt: P61769)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight45059.8
Non-Polymers*Number of molecules7
Total formula weight434.5
All*Total formula weight45494.2
*Water molecules are not included.

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PDB entries from 2024-11-06

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