4U1A

Crystal structure of human peroxisomal delta3,delta2, enoyl-CoA isomerase helix-10 deletion mutant (ISOB-ECI2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Enoyl-CoA delta isomerase 2	polymer	270	29847.1	3	UniProt (O75521) Pfam (PF00378)	Homo sapiens (Human)	DRS-1,Delta(3),delta(2)-enoyl-CoA isomerase,D3,D2-enoyl-CoA isomerase,Diazepam-binding inhibitor-related protein 1,DBI-related protein 1,Dodecenoyl-CoA isomerase,Hepatocellular carcinoma-associated antigen 88,Peroxisomal 3,2-trans-enoyl-CoA isomerase,pECI,Renal carcinoma antigen NY-REN-1
2	D, E, F (A, B, C)	CHLORIDE ION	non-polymer		35.5	3	Chemie (CL)
3	G, H, I (A, B, C)	water	water		18.0	37	Chemie (HOH)

Sequence modifications

A, B, C: 103 - 349 (UniProt: O75521)

PDB	External Database	Details
Met 80	-	initiating methionine
His 81	-	expression tag
His 82	-	expression tag
His 83	-	expression tag
His 84	-	expression tag
His 85	-	expression tag
His 86	-	expression tag
Ser 87	-	expression tag
Ser 88	-	expression tag
Gly 89	-	expression tag
Val 90	-	expression tag
Asp 91	-	expression tag
Leu 92	-	expression tag
Gly 93	-	expression tag
Thr 94	-	expression tag
Glu 95	-	expression tag
Asn 96	-	expression tag
Leu 97	-	expression tag
Tyr 98	-	expression tag
Phe 99	-	expression tag
Gln 100	-	expression tag
Ser 101	-	expression tag
Met 102	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	89541.2
Non-Polymers*	Number of molecules	3
	Total formula weight	106.4
All*	Total formula weight	89647.5

*Water molecules are not included.