4U0A
Hexameric HIV-1 CA in complex with CPSF6 peptide, P6 crystal form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Capsid protein p24 | polymer | 231 | 25461.3 | 1 | UniProt (P12493) Pfam (PF00607) Pfam (PF19317) | Human immunodeficiency virus type 1 group M subtype B (HIV-1) | Pr55Gag |
| 2 | B (B) | Cleavage and polyadenylation specificity factor subunit 6 | polymer | 15 | 1550.8 | 1 | UniProt (Q16630) | Homo sapiens | Cleavage and polyadenylation specificity factor 68 kDa subunit,CPSF 68 kDa subunit,Pre-mRNA cleavage factor Im 68 kDa subunit,Protein HPBRII-4/7 |
| 3 | C (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 147 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P12493)
| PDB | External Database | Details |
|---|---|---|
| Cys 14 | Ala 146 | engineered mutation |
| Cys 45 | Glu 177 | engineered mutation |
| Ala 184 | Trp 316 | engineered mutation |
| Ala 185 | Met 317 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27012.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 35.5 | |
| All* | Total formula weight | 27047.5 |
