4TWF
X-ray structure of a pentameric ligand gated ion channel from Erwinia chrysanthemi (ELIC) in complex with bromomemantine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Cys-loop ligand-gated ion channel | polymer | 307 | 35281.2 | 10 | UniProt (P0C7B7) Pfam (PF02931) | Dickeya chrysanthemi (Pectobacterium chrysanthemi) | ELIC |
| 2 | K, L, M, N, O... (A, B, C, D, E...) | Bromomemantine | non-polymer | 258.2 | 12 | Chemie (BR7) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J: 11 - 317 (UniProt: P0C7B7)
| PDB | External Database | Details |
|---|---|---|
| Ala 152 | Ile 152 | conflict |
| Gly 164 | - | insertion |
| Ser 247 | Phe 246 | engineered mutation |
| Asn 289 | Met 288 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 352811.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 3098.4 | |
| All* | Total formula weight | 355910.3 |
