4TVG
HIV Protease (PR) dimer in closed form with pepstatin in active site and fragment AK-2097 in the outside/top of flap
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | HIV Protease | polymer | 99 | 10831.8 | 2 | UniProt (Q90EA1) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | C | Pepstatin | polymer | 6 | 685.9 | 1 | BIRD (PRD_000557) | synthetic construct | |
| 3 | A | 3-(morpholin-4-ylmethyl)-1H-indole-6-carboxylic acid | non-polymer | 260.3 | 1 | Chemie (K97) | |||
| 4 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: Q90EA1)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 7 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 22349.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 352.4 | |
| All* | Total formula weight | 22701.9 |
